1. Insectoacaricides.
2. Derativational funds.
The body of arthropods is a specific environment where the pathogens of diseases, besides the mechanical presence, may pass the phases of their development, accumulating biomass, preparing for the change of the owner. With their help, the pathogens of bacterial infections are transmitted, such as tularevia, brucellosis, leptyosis, leptospirosis, protozoal and helminthous.
Insectoacaricides - preparations of chemical or biological origin designed to combat harmful insects and ticks.
By origin, they are divided into: phosphorodorganic compounds, chlororganic compounds, carbamates, synthetic pyrethroids and preparations of different groups.
Of the total volume of spent insectoacaricides, the FOS accounts for 43%, HOS - 17%, carbamates -25%, of the other 15%.
Different arthropods, as well as intermediate forms of their development are not very sensitive to pharmacological agents. Therefore, in addition to general concept Insecticidal influence distinguish the actions:
ovyocidal - the destruction of insect eggs, Larvicidal - the destruction of larvae and caterpillars, acaricidal - the destruction of ticks, pesticide - a wide range of action. Substances that scare insects from animals are called repellents, and means attracting insects - attractants.
In the paths of penetration into the body of insects, they are divided into contact, reading in hemolyimph through the insect cuticle; intestinal insecting insect through the digestive apparatus, and fumigant penetrating through breathe-helping machine. AT last years Attention is paid to system action insecticides. The animal enteral or parenterally entered into the organism in harmless doses for it, systemic insecticides are lichnic by the larvae migrating in the tissues of the animal.
Requirements for insectoacaricides:
1. Have a specific effect on arthropods at all stages of development, and when using minimum doses;
2. Enjoy a persistent ability;
3. maintain effectiveness in various meteo conditions;
4. Efficiency;
5. Security for service personnel;
6. Do not have a remote effect effect.
If a few years ago, their toxicity and resistance in the environment were a major indicator, then today there is a distant effect of action: mutagenic, teratogenic, carcinogenic, etc.
Insecticide action mechanism is different. Some of them break insect chitinic cover, others change the function of respiratory or digestion. But the most effectively violation of individual metabolic links after resorption of drugs is most effective.
Insecticides are used by natural conditions In places of clusters and flows of insects, indoors and on the body of animals.
They are used by spraying, pollinating, applying to the surface of the body using rugs (watering animals along the spine compositions of organic solvents and pesticides), bathing of animals and aerosol treatment.
Insectoacaricides are used in the form of solutions, emulsions, lotions, suspensions, powders (healing), aerosols, porons, insecticidal ointments, insecticidal pencils, insecticidal soaps, zooshampune, films, tags, ear numbers, collars, flue checkers.
The type of habitat of arthropods and the phase of ontogenesis determines the choice of means of struggle:
* When combating sarchpotoid ticks - the downturn and spraying of animals;
* with gnus and blindders - checkers, pills, cords, aerosol preparations;
* with lshami and flea - insecticidal powders, shampoos, various soaps, etc.
In connection with the prohibition of the use of persistent and highly toxic chemical compounds, the sanitary and toxicological importance of these pesticides, however, their danger for live objects of nature is still quite high, which is pernicably reflected on the external environment.
The treatment requires clarity, punctuality, the correctness of the preparation of working solutions, compliance with the deadlines and doses of their application. Special attention It should be compliance with the conditions of personal hygiene and compliance with these requirements by all animal husbandry workers. The doctor should well know the toxicity of insecticides for animals and, in case of the very first signs of poisoning, it is quickly applied to an antidote.
Phosporganic connections.
The compounds of this group are esters of a row of acids: phosphoric, thiophosphoric, dithiophosphorus.
The advantages of the FOS are a wide range of insecticidal action, low resistance in objects of the external environment.
Two groups: contact and system action.
The contacts of contact action include chlorofos, trichlorometaffos -3, carbofos, bytex, metaphos, puzalon, garardon, neocidol, etc.
To systemic drugs - antio, amifos, phosphamide, phospholidone, etc.
Some drugs - phosphamide, antio, have contact and systemic effect.
Under the influence of physical and chemical factors of the outer environment, the FOS is subjected to isomerization, translacylation, in which more active and toxic compounds are formed in the PPRotsess. In the body, they are subjected to oxidative desulfurization (sulfur cleavage associated with the phosphorus atom and replacing it with oxygen), possibly the formation of conjugates with glucuronic and sulfuric acids, glutamine. FOS is allocated in an energous form through respiratory bult (20 - 25%), with urine (30%).
The mechanism of action of the FOS on insects and mammals is the same and lies in the inhibition of cholinesterase, which leads to an excessive accumulation of acetylcholine and disruption of the transmission of nerve impulses, which is expressed by short-term excitation, and then by paralysis nervous system.
Insects have a body tremor (mainly limbs), a disorder of coordination coordination with loss of ability to fly, paralysis, death.
Chlorofos (Negulon, Diptext)
White crystalline powder, well soluble in water and most organic solvents.
Definitely acts on insects and helminths. Apply for processing animals against flying insects. Cows are treated after the boobs. It has high systemic activity. It kills the larvae of the hedges in the tissues of the animal, not only with internal, but also in external use.
Hydromemin - chlorophos.
Hypodermini- chlorophosum.
11.6% chlorophos alcohol solution.
Transparent yellowish color liquid with a slight aromatic smell. Apply against the larvae of the subcutaneous fusion by watering a cattle in a dose of 16 ml - animal weighing up to 200 kg and 24 ml - with a greater mass.
Dioxafos.
Dioxaphosum.
16% chlorofos solution in an organic solvent. Dose is 12 ml and 16 ml (similar to the hypoderaminechlorofosu).
DDVF (Dichlorfos Dichlofos)
Transparent colorless or weakly yellow liquid, poorly soluble in water.
It has a selective effect on insects, ticks, helminths.
Carbofos.
Colorless liquid. Used in the form of 1% water emulsion and 4% of the dust, shampoo "Pedilin" - to combat eggs and larvae of lice, carbosol aerosol.
Diazinon
Diazinonum (neocidol, Bazudin).
Colorless oily liquid, poorly soluble in water.
Released in the form of 25 - 60% of the emulsion concentrate, 40% wettable powder, 5% of the dryer.
Dursban, sulphidophos, foxime, trichloromethophos, phthalofos, etc. are also used.
Chlororganic connections.
Chlororganic compounds are a group of drugs used in agriculture with various purposes. In the vetertains, chlorofolded cyclic hydrocarbons are most often used.
The characteristic feature is high persistence, i.e. resistance to the effects of environmental factors.
These are lipotropic substances.
These are mainly powders, less often liquid, poorly soluble in water, good in organic solvents and oils.
Insktoacharicidal mechanism:
it is easily penetrated into hemolyamph, tissue cells are dechlorized to form free radical and peroxidant compounds that destroy cellular structures. As well as the FOS is blocked by acetylcholinesterase.
Until recently, GHCG was used. Since 1989, its use is prohibited.
Aurican
Auricanum. Ear drops (Hungary).
Larous liquid with a small opalescence.
Due to the multicomponent composition, it is effective for diseases of the ears in dogs and cats (microbial otitis, detectation).
I bury 10 drops into each ear for 7 days.
prednisolone sodium - 0.03 g;
hexamidine isotionate - 0.05 g;
tetrakain hydrochloride - 0.2 g;
lindane (GHCG) - 0.1 g;
xylene 0.5 g;
glycerin - 2 g;
distilled water up to 100 ml.
Gamma isomer hexachlorcyclohexane (Lindane)
Crystalline white-cream powder with a specific smell.
Apply in combination with Colavin.
Folbex (AKAR - 338). In its pure form - light yellow crystals. Well soluble in alcohol. Used to combat varro-bees.
Carbamates.
Biological activity is very close to the FOS, inhibit the cholinesterase.
The positive property is relatively fast decomposition in the external environment.
In the vetporates, we found an application:
Baigon (Proskur, Wound, Apr rubb).
White crystalline substance, well-soluble in organic solvents.
Effective tool Fight against mosquitoes, flies, cockroaches and other insects, as well as ticks. Against mosquitoes and flies used in the form of 2% of the aqueous emulsion with a consumption rate of 100 ml / m 2.
The release form is 80% and 20% of the emulsion concentrate, 1% of the Dust and other forms (Bayer).
Baffo-powder (1% absorption) - animals divert 2 - 3 times a week;
Buffo-shampoo - the checkout for 5 - 10 minutes;
Baffo collar;
Balfo Spray (Baltonys), etc.
Sevin
White powder insoluble in water is produced in the form of 50 - 80% wetting powder or 7.5% of the dryer.
It is used in the form of 0.5 - 1% suspension, in the form of 2% and 7.5% of the hectares.
Sulfur preparations.
Sulfur and its compounds belong to the most important classes of pesticides. The introduction of sulfur to organic acaricides leads to an increase in the efficiency and reduction of the toxicity of the drug for warm-blooded animals.
The sulfur as an element almost does not act on the animal organism, but interacting with alkalis and proteins, turns into active compounds. On the skin and in the digestive tract there are all conditions for the formation of such active compounds. For example, when using sulfur on the skin, hydrogen sulfide and partially sulfur arhydride are partially formed, which act acariculate, antiseptically and irritate skin exterorceptors.
It is known the presence of biologically active properties in organic sulfur-containing compounds: thiophenols, sulphides, disulfides. Aromatic disulfides are inherent in strong acaricidal properties.
Purified sulfur
Sulfur Depuratum.
Lemon yellow powder.
She caresses for the treatment of scabies, trico, dermatitis in the form of 10 - 30% of ointments, line, dusts. When taking inside, interior intestinal interiors, which contributes to the manifestation of the laxative action. Apply it both as antidot under a number of poisoning.
cattle - 100 - 200 g;
small cattle - 50 - 100 g;
dogs - 10 - 15 g;
pigs - 15 - 25 g
Sulfur precipitated
Sulfur Praecipitatum.
The smallest powder, easily suction when prescribed inside, which can lead to poisoning. It is used externally in the form of 5 - 20% of ointments.
Sodium thiosulfat
Natrii Thiosulfas.
White crystalline powder, well soluble in water.
When intravenous administration, an aitoxic, anti-inflammatory, antido-remote effect (with cyanide poisoning, heavy metals) has an anoxic. It is one of the components of the Demyanovich tool, used for the treatment of scabies (first affected areas are treated with a 60% sodium solution of thiosulfate, after drying, a 10% solution of HCl is applied).
Unitiol
Release form - powder, tablets of 0.25 and 0.5 g, amplule 5% solution in ampoules of 5 ml.
Dose with in / in the introduction of 10-20 mg / kg.
In addition, the sulfur and sulfur-limestone dust, colloidal sulfur, sulfur colloid paste.
Plipoly (diphenylsulfide).
They are obtained as a by-product in the production of coal fenas.
Homogeneous dark oily liquid.
It is used as an acaricide for the treatment of sheep in the form of 0.5 - 1% emulsions.
Lepran - a sulfur-containing coal resin processing product containing 10 to 14% benzothiophene.
Dark brown liquid with a smell of coal oil.
The drug can be used to anticipate the dry and lactating sheep.
Question 5.
Pyrendines and Pyretrians.
Pyrethrum is the "Persian" powder, which by speed of action on insects and harmlessness is one of the best preparations.
It is obtained from perennial species Dolmatskaya and Caucasian chamomile. The active substances of Pyrerum are six close to each other chemicals: Pyrethrin - 1, Pyrerin - 2, Cirerin - 1, Cirerin - 2, Jasmolin - 1, Jasmolin - 2, combined under the same name - Pyrendines.
Currently, analogs are particularly intensively investigated. natural connections - Synthetic pyrethroids whose production exceeds 3000 tons per year - permethrin, cypermethrin, butoxy, phenvalerat, etc.
The advantage of Pyretroids is that they have high insecticidal properties that are explained by almost instant killing action, they are harmless to humans and animals, since getting into the body is rapidly metabolized.
A significant disadvantage limiting the practical use of many synthetic pyrethroids is their instability in the light and in the presence of atmospheric oxygen.
These are the poisons of neuro-paralytic action. The death of insects occurs as a result of excessive stimulation of the central and peripheral nervous system (stimulation of sensory, central and motor axons) - the molecules are wedged into Na + conductive channels, etc. Increases sodium current. Channels cannot return to its original state. As a result, Akson is polarized all the time, which leads to his death as a result of hyper-excitation.
One of the properties resulting in high insekicidal activity is their pronounced lipophilicity, which increases the flow of pyrethrines into the insect organism.
Insecticidal activity is enhanced with a decrease in temperature, and almost disappears at temperatures above 30 o.
In connection with the use of pyreteroids in very small doses, they mostly meet the requirements of protection ambient And in the smallest degree conjugate with the probability of pollution of animal products pesticides.
Permetrin (Ambush, Corsair).
Preparative forms:
stomasan - 20% concentrate of emulsion;
crereopyr is a composition of Creolain and 2% permethrin or 2% stomasan;
anometric H - 20% emulsion concentrate;
porol - 2% permethrin emulsion on dioxanole.
Typermethrine (Tsimbush, Ripcord, etc.)
Preparative forms:
kinmix - 25% emulsion concentrate;
cracin - 2% Kinmix Emulsion on Cylias;
dust "Tsimal";
insecticidal pencils "Inay", "Nika", "Virbers", etc.; Typerol aerosols, "Cide".
Decamerin (deltamerin).
Preparative forms: decis, butoxy.
Biologically active substances possessing inhibitoacaricidal properties.
Avermectin
A complex of eight people in chemical relations representing a 16-membered macrolide lactone, connected to two sugar residues of oleandrosis. This is a product of vital activity of Streptomyces Avermitilis.
Ivermectin -a semi-synthetic hydrogenated derivative of abamectin.
Doramectin - Natural fermentation product Streptomyces Avermytilis.
Moxidectin - semi-synthetic product derivative formed by STR. Cyaneogriseus (no sugar residues).
The following preparations containing ivermectins and avermectins are used:
yvesek 1% injection;
yvesc 0.5% Poor;
dotin (1% solution of abamectin);
baymek 1% injection;
dearthax 1% injection;
aversect 2% injection;
ointment Aversectinic;
moxidectin 1% injection.
Pharmamedine compounds
Amitraz
White crystalline substance, poorly soluble in water. In the body is metabolized. Inhibits A 2 - adrenoreceptors.
Safe for ruminants, but toxic for horses.
The emulsion concentrate is used for the purchase and spraying of cattle against ticks and lice in a concentration of 0.02%; For spraying pigs 0.05 - 0.1%; Dogs and cats 0.05%.
His dosage forms:
amitrazine, land, Leda, etc.
Benzylphenylmochin derivative
Program- Insecticide of system action.
Release form - tablets (red - 67.8 mg DV; gray - 209.4 mg dv), suspension in capsules (orange - 135 mg of DV; green - 270 mg of DV).
Cats and dogs inside 2 - a multiple with an interval of 30 days:
dogs - 10 mg / kg. m. (Tablets);
cats - 30 mg / kg. m. (capsules).
Repellents
From Latin Repello - repulse, distingalizing, substances that scare arthropods from animals and birds.
Apply mainly to protect animals from attacking bloodsowing insects, prevention of transmissible diseases.
In modern practice as R. Used mainly chemicalshave a long time actions - simple and esters, alcohols, aldehydes, amides, essential oils.
The R. olfactory, or fumigans (volatile substances) differ on the nerve endings of the olfactory bodies of arthropods and prevent them from choosing an attack object (dimethylphthalate, diethyltolumide, kuzole, etc.); anticontuple or contact, acting on taste and olfactory insect organs with direct contact with the treated surface (gasoline, indon, etc.); Masking or deodorizing, which neutralize or destroy odors that attract insects (lemon oil).
Most R. refers to the class of low-toxic for warm-blooded animals, in connection with which many of them, for example, benzimine (hexamide), diethyltoluamide (DETA), drugs P - 203, RV - 5, dimethylphthalate, indon, kuzola, oxamat is used in veterinary medicine .
The method of low-volume, fine-coil and aerosol treatment, in which the bulk of R. enters the hair cover of the animal, which prevents the suction of drugs through the skin, reduces the risk of milk pollution. It is prohibited to process animals with impaired skin integrity. When entering the mucous membranes of the eyes, the nose, the mouth R. cause irritation.
Attractants
From Latin ATTRAH - attracting to myself.
Baits, specific substances that attract insects and used to combat them.
Unlike repellent, A. have strict specificity, attract only a certain type of insects.
Bloss a.: Gulf (attract individuals of the opposite sex), food (as a power source) and A. - substrate for laying eggs. The greatest value They have sexual A., highlightable with females and insect-related insect pheromones (BAV, stimulating sexual behavior). For example, sexual A. are isolated from females of unpaired and black American silkworms. Various chemical compounds (carbon dioxide ammonium, complex phenyl esters, amines, etc. also have attractive properties.
In the fight against flies and cockroaches, liquid and dry food A. in conjunction with insecticides were widespread.
Of particular interest are A. in gaseous form. For example, carbon dioxide for attracting mosquitoes, midges, ticks, as well as light traps (using UV rays) used for the catch of mosquitoes, midges, hoarses in the evening and night.
A. Apply during the survey of the area to the infection of pests, as well as for the immediate destruction of harmful insects.
An insectoacaricidal means is described, which contains a composition from fipronil and alfactory as active substances at their concentration into wt.% common lineup Funds: fipronil 0,01-10.0, alphabipermetrium 0,01-10.0, with a ratio of mass fractions of 1 part of the fipronil to 0.1-20 parts of the alpha phantimmer. The invention can be used to combat carriers of various transmissive and skin infections, to destroy insects in places of pets, destroying home dust ticks that increase the allergenic load on the organism of animals and humans. The tool can be used in the form of lotion, solution, spray, droplets for topical use, air conditioner for wool, etc. 7 zp F-lies, 1 tab.
Prevention of natural focal infections of viral, bacterial, protozoa and ricketer etiology, whose causative agents are transmitted by ixodic ticks ( tick-borne encephalitis (CE), borreliosis (ICB)), is a problem for health care. The largest epidemiological in the spread of animal diseases (piroplasmosis, borreliosis, detectation, demodecosis, sarkopotidosis, notooderosis, "hanging itching") have representatives of the Ixodidae Argasidae families, Sarcopnidae and Demodicidae. Modern prevention of tick-borne infections is based on the non-specific protection of people and animals from attacking ticks, infections carriers, since there are no vaccines against most of these infections. This task is solved by using acaricidal agents for individual protection.
Therefore, the actual task of modern veterinary and medicine is the development of insurgelient funds, which would have the properties of fast, reliable protection against the large spectrum of insects and ticks, would have low toxicity and quite a long action.
To combat insects, predominantly compounds relating to pyreteroids, phosphorodorganic drugs, carbamates and heterocyclic derivative are used. Ready-made forms of drugs containing one compound as a active substance, usually have a relatively narrow spectrum of insecticidal activity, a short time Protective action and lead to rapid development in populations of insect resistance to the active substance.
Existing combined insecticidal preparations along with sufficiently high efficiency also have a number of significant drawbacks, because often do not take into account the set of properties of compounds associated with the mechanism of action, spectrum of action, the beginning of the effect, the duration of the effect, the circulation paths and removal from the body, toxicity, stability when used on the skin on the surface of various materials (photostability, enzymatic lability), etc. .
The composition for the treatment of arachnentomoses, which contains fipronil and esefenvalerat as active substances (RF Patent 2181243, 2002). The disadvantages of the composition are a limited range of destination - for the treatment of arachnentomoses in animals and the inactivity of esefenvaleratus for taiga ticks. The effect of temporary increase in the aggressiveness of the ticks is possible due to the esephenvalerat, which increases the risk of bites and accelerate the sinking of the ticks in the original moment of its entry into the skin of an animal or hum.
The insectoacaricidal composition for a mammal, containing fipronil and benzylbenzoate as active substances (Patent of the Russian Federation 2283590, 2006) However, the benzylbenzoate and fipronil do not have a rapid contact action, they are acceptable only for funds with long-term applications and with the possibility of long-term contact with insects for manifestation Sufficient insectoacaricidal activity.
A acaricidal agent containing a mixture of alphabipermethrin and diacyldimethylammonium bromide as a active substance is known. It uses alphazipermetrin in the amount of 0.01-0.15% (RF Rhbest 2242967, 2004). The disadvantage of this means is the use of a quaternary ammonium compound (hour) - Didecyldimethylammonium border, which acts as an antimicrobial and disinfectant, but not significantly affecting the extension of the effect or expanding the spectrum of acaricidal activity. This combination allows you to expand the indications for the use of the means due to the combination of insecticidal and disinfectant properties of the components, but does not change the insecticidal characteristics of the means.
A acaricidal agent is also known, including imiprotrin and alphabipermetrin (RF Patent 2280983, 2006). The disadvantages of this means are that for both components is characterized by a quick roofing effect, but they do not have a sufficient duration of the insecticidal action associated with the specificity of penetration and distribution in the animal body. Therefore, this combination will be effective for processing surfaces to protect primarily from cockroaches, ants, etc. Due to the rapid contact action, it will not be sufficiently effective to provide a prolonged insectoacaricidal action when applied to the skin and / or animal wool.
The proposed insectoacaricidal agent is devoid of disadvantages inherent in well-known combined means, due to the fact that it contains a composition from fipronil and alfactory as active substances at their concentration in wt.% In the total composition of the funds:
At the same time, the ratio of mass fractions of fipronil and alfactory, depending on the form of the preparation, can vary from 1 to 0.1 to 1 to 20, respectively.
Pyretroid Alfajipermetrin is a mixture of two enantiomers (1R) - Cis - S and (1S) - Cis - R in a ratio of 1: 1. It has a high acaricidal activity, the rapid beginning of the action, dramatically limits the movement of ticks over the surface, does not cause acceleration of the suction of ticks to the animal.
The disadvantages of alphabipermetrine are: destruction under the action of the UV of the Sun (photolability), relatively high toxicity for animals, irritating effect, deep penetration through the skin, moderate persistence and excretion from the body not only through skin and hair, i.e. Relatively rapid decrease in concentrations in outer tissues and reduced contact impact.
When applied to the skin, fipronil is localized in the sebaceous glands, not falling into the blood of the animal. Thus, the effect of the "reservoir" is created, which provides a long action and maintaining efficiency when bathing an animal with shampoo. The fipronil applies to the skin and wool skin. The prolonged effect of sunlight on the drug, applied to walls, materials or animals, does not reduce the efficiency of the drug.
The invention uses a composition of substances with a rapid (immediate) and slower (delayed) acaricidal and insecticidal lethal effect.
The use of a fipronil superior to the alphabipermethrin on the duration of the effect and characterized as less toxic (less irritant) for humans and animals compound reduces the total toxicity of the fipronil composition and alphabipermetrium while maintaining activity and efficiency. Fipronil and Alphazipermetrin complement each other and for other indicators important for practical use to protect different species Animals, when used in different seasons, ensure the effect of synergies, increase the universality of the insectoacaricidal activity of the composition.
Table 1 presents the results of studying the properties of solutions of individual substances of fipronil and alphabipermetrin in comparison with their composition with respect to adult forms of ixodic ticks (Ixodes Persulcatus and Ixodes Ricinus).
Designed ready-made forms of insectoacaricidal agents based on the use of a combination of fipronil and alphabipermetrine, provide more reliable protection of animals and people from attacks of ticks than monolaying these substances, repellent agents and compared known analogues.
One of the finished forms of the insectoacaricidal agent are drops for topical use (drip application on the skin, for example, on the animal knee), intended for long-term animal protection from ticks and insects (from 2 weeks or more). The drops contain fipronil in the concentration of wt.% At least 0.5% (preferably 7%) and alphabipermetrin at the concentration of wt.% Not less than 0.25% (preferably 1.0%).
The finished form in the form of a lotion, a solution, spray for applying to wool, skin, the clarification of birds has an insector-deplege effect with a repellious effect of at least 3 hours and with an insectoacaricidal effect of at least 1 week and contains fipronil at the concentration of wt.% Not more than 1% (preferably 0.1%) and alphabipermetrin at the concentration of wt.% Not more than 1% (preferably 0.1%). Additionally, the composition of this form includes repellents, such as Ring and / or Deta, with a total mass fraction of repellents at least 5%.
This formation is used by an aerosol propellant or unplanned type of spraying or direct application with a napkin, mittens, etc., to ensure an insecoelectric effect in order to protect animals from insect attacks and ticks in the spring-autumn period when walking in the forest and so on. p., for targeted local application for the purpose of direct destruction of suiced (ticks) or insects. It can also be used for outdoor treatment Armbands to protect wounds from flies.
Liquid shape (solution, lotion, emulsion) for use as a spray for processing animal content with an effect duration of at least 1 week (10-14 days) contains fipronil at the concentration of wt.% Not more than 1% (preferably 0.1%) and alpha quirererin in the concentration of wt.% Not more than 1% (preferably 0.3%).
Such a form of means is used to handle curtains, anti-organic grids, walls, bedding, etc. in tourism conditions, fishing, hunting and labor activity, on vacation, on farms, in the stables, in aviaries, in other economic and residential premises, in competitions at high numbers and activity of blood-suicing insects and ticks; To protect against insects spreading through rodents.
Each of the listed forms may additionally contain benzylbenzoate as a valid component in the working concentration of wt.% Not less than 0.1% (preferably 1%) and / or Melia extract (Mélia Azedárac L.) at the concentration of wt.% Not less than 0.1 % (preferably 0.5%). Also additions of fir and / or vanillin essential oil for aromatization, deodorization and enhancement of the repellent effect are also possible.
Each of the listed forms (preferably a composition for Topical use) can be used to include a collar obtained from polymer, natural or combined materials. When wearing the collar of animals, a protective insectoacaricidal effect is ensured.
The finished form in the form of an air conditioner for wool in the form of a balsam or spray combines a short acaricidal effect (2-3 days) with cosmetic-hygienic properties: provides efficient dry cleaning of wool (improving combing, decreased hair confusion, combing and mechanical removal insects), antifungal effect, decrease in the formation of dandruff. Balsam contains fipronil at the concentration of wt.% Not more than 0.1% (preferably 0.02%) and alphazipermetrin at the concentration of wt.% Not more than 0.1% (preferably 0.02%) and further comprises acting components - benzylbenzoate in concentration wt.% Not more than 1% and Melia extract (Mélia Azedárac L.) at the concentration of wt.% Not more than 1%. As additional auxiliary components that provide easy combing wool and other cosmetic-hygienic effects, air-conditioning additives are used, such as cellulose derivatives and silicones.
The tool can be produced as a concentrate in a liquid form, which is divorced before use to the recommended working concentrations. The content of fipronil in the concentrate is up to 5% (preferably 1%), alphabipermetrina - up to 10% (preferably 5%). The content of benzylbenzoate in the concentrate can be up to 10%, Melia extract is up to 3%.
Before use, the concentrate is divorced at 20-30 times in water and is used by an aerosol or other method of applying to the processed surfaces.
Acaricidal drops (composition for Topical use)
Reception
Auxiliary components up to 100 ml: PEG 400, ethyl alcohol, isopropyl alcohol, antioxidant, PEG 40 hydrogenated castor oil, lavender essential oil.
Received result
The drug provided insectoacaricidal protection against tick attacks at least 40 days, from fleas at least 60 days.
Spray InsectorPelection
Reception
Auxiliary components up to 100 ml: PEG 400, ethyl alcohol, isopropyl alcohol, antioxidant, povene, PEG 40 hydrogenated castor oil, lavender essential oil.
Appointment and method of application
The remedy was used in the packing on a free-free basis with a spray nozzle for applying a drug in the form of a spray. The bottle holds vertically, directing spraying from a distance of 10-25 cm against the growth of wool (lifting long wool), if necessary, process ammunition and animal clothing (back, etc.). Processing is performed before walking in places with a high risk of insect attacks (especially ticks) at the rate: for cats and dogs - 2-3 ml per kg of weight, for horses 60-120 ml for complete treatment. When processing, it was taken into account that one press of the spray spray corresponds to 0.7 ml of the drug. It is necessary to avoid entering the eyes, mucous, open wounds, so in these places to distribute the tool with great accuracy, for example, with a napkin or sponge.
Received result
The repellent effect was formed immediately and persisted on wool up to 8 hours, on tissues up to 5 days. Acaricidal protection The means provided at least for 10 days.
When applied to the wound bandage (aerosol to light wetting bandage), the drug provided protection against flies by no less than 6 hours.
Insectoacaricidal solution for animal content
Reception
Auxiliary components up to 100 ml: PEG 400, ethyl alcohol, isopropyl alcohol, antioxidant, povidone, PEG 40 hydrogenated castor oil, lavender essential oil, denature (bittex).
Appointment and method of application
The remedy was used in the packing on a free-free basis with a spray nozzle for applying a drug in the form of a spray. The bottle holds vertically, directing spraying from a distance of 20-30 cm on the processed surfaces (floor, walls, bedding, a native, aviary, coneer, etc.).
Received result
The drug provided protection against the propagation and attacks of various insects and ticks in the places of animal content for at least 2 weeks.
Insectoacaricidal concentrate for preparing a solution for processing animal content
Reception
Auxiliary components up to 100 ml: PEG 400, ethyl alcohol, isopropyl alcohol, antioxidant, PEG 40 hydrogenated castor oil, lavender essential oil, denature (bittex).
Appointment and method of application
The drug is used to process animal content places to protect against flying and non-flying insects (mosquitoes, midges, hoarses, flies, heaps) and ticks.
Apply for processing curtains, anti-marvel grids, walls, ceilings, canopies, beetles, ammunitions, etc. On farms, in the stables, in aviaries, in competitions, in conditions of tourism, fishing, hunting and under loads, on vacation, with high numbers and activity of insects and ticks. Destroys arthropods, prevents their reproduction and distribution through carriers - rats, etc.
Before use, the concentrate is divorced at 20-30 times with water (0.5 liters of concentrate by 1-1.5 bucket of water). The degree of dilution (20-30) depends on the activity of insects and ticks. Mixing is carried out in a clean capacity by introducing a concentrate into water with constant stirring. Storage in a divided form before use for no more than 10 hours, stirred intensively before applying.
It contains bitterness (bittex) to protect the treated surfaces from licking and expanding animals.
The diluted agent is applied with an aerosol method (using any fixture for fluid aerosol) on the surface-processed surfaces or apply with napkins.
Processing is carried out at the rate of 10-20 ml of the diluted agent per 1 m 2.
Consumption: 1 bottle of 0.5 liters are divorced by 1-1.5 buckets, which is sufficient for processing from 500 m 2 to 1.5 thousand. 2.
Received result
The duration of the insectoacharicidal effect is at least 10 days.
Air Conditioner for Wool with Insectoacharicidal Effect
Reception
Auxiliary components up to 100 ml: ethyl alcohol, isopropyl alcohol, PEG 400, water, polyvartenium-10, DC 5330, antioxidant, PEG 40 hydrogenated castor oil, lavender essential oil.
Appointment and method of application
The tool combines insectoacaricidal properties with cosmetics and hygienic characteristics. Use for dry cleaning wool - combing combing, hair confusion is reduced, making combing and mechanical removal of insects. The remedy was used in a package on a non-flimple-based basis with a pale nozzle for applying a drug in the form of a spray. The bottle holds vertically guiding spraying spray from a distance of 10-25 cm against wool growth, lifting long wool. Processing is performed before the animal walk at the rate: for cats and dogs - 2-3 ml per kg of weight.
Received result
The drug provided an insectoacaricidal protection against tick attacks at least 3 days. The drug facilitates combing hair and mechanical tick removal after walking. In addition, when using the drug, a decrease in dandruff formation is noted.
Insecticidal Effect Collar
Reception
It is a polychloroquinyl tape impregnated with an insectoacaricidal composition corresponding to the composition of the composition for topical use, at the rate of 0.7-0.8 g of the active substance per 10 g of tape. The collar is packaged into a hermetically closed package embedded in individual consumer packaging.
Appointment and method of application
Used for long-term protection against fleas, from ticks.
To put on the collar on the neck of the animal (dog, cat) at least one day before going to the place where there is a potential attack of ticks. Before walking in places of large clusters of ticks, additionally process the limbs of the animal by sprays. The use of a collar to increase the efficiency of protection against ticks is optimally combined with other forms of the drug similar purpose in the form of droplets or spray.
Received result
The active components that are part of the collar gradually released from the surface of the ribbon are transferred to the hair cover of the animal and have an insectoacaricidal effect on insects and ticks. As a result, the collar provided defense against fleas for 3 months, from ticks of 1.5 months,
All means from the above examples, subject to recommendations for use, does not provide local irritating, skin-resorbative and sensitizing effects.
In all cases, the proposed combination of insectoacharicidal components provides:
The synergistic effect manifested in increasing the efficiency of insektoacharicidal action in comparison with monocomponent facilities,
Expansion of testimony to the appointment,
Acceleration of the beginning and prolongation of insectoacharicidal action in comparison with monopreparations.
Adding repellents into the composition of finished forms of means increases their acaricidal efficacy and causes the presence of a protective effect against bloodsowing flying insects.
| Table 1. | ||||
| Comparable properties and characteristics | Solution of fipronil 200 μg / ml | Alfaization solution 200 μg / ml | Composition Fipronil and Alphazipermetrin 200 μg / ml | |
| The beginning of the acaricidal effect in vivo in Topical application, hour | 20 ± 4. | 2,0 ± 0.5 | 1.0 ± 0.2. | |
| The duration of the effect of in vivo in Topical application, day | 5 ± 0.5 | 1.5 ± 0.5 | 9 ± 1,5 | |
| Efficiency of acaricidal action when contacting ticks with treated fabric | LD 50 μg / g | 0.29 ± 0.06. | 0.23 ± 0.05 | 0.19 ± 0.04. |
| Mortality in an hour,% | 10 ± 1,2 | 42 ± 2.6 | 63 ± 3.1 | |
| Mortality after a day,% | 90 ± 4.2. | 94 ± 4.3. | 100 | |
| The effect of reducing the activity of ticks by the time of suction, min (when monitoring the placebo 5 min) | 10 ± 1. | 18 ± 2. | 32 ± 2. | |
| Ways of distribution and excavation from the body with external use | Through the skin and blood flow. Cumulation and selection through the sebaceous glands | Selection through the skin, cal, urine | The excretion is predominantly through the skin, sebaceous glands. | |
| Photostability, spectropometrically on the dynamics of reducing the area of \u200b\u200bpeak in the UV region after exposure in the sun | High | low | high | |
| Sensitivity to enzymes | Low | high | moderate | |
| Toxicity | - refers to the IV class of danger according to GOST 12.1.007-76 - MPC in the air working area - 0.01 mg / m 3 | - refers to the IV class of danger according to GOST 12.1.007-76 - PDC in the air of the working area - 0.5 | - Refers to the IV class of danger according to GOST 12.1.007-76 - PDC in the air of the working area - 0.5 mg / m 3 | |
| Skin-annoying and sensitizing effect (drip method, exposure time 24 hours) | - No Absence | - Moderate Absence | - weak Absence |
CLAIM
1. An insectoacaricidal agent containing a composition from fipronil and alphabipermetrium as active substances at their concentration in wt.% In the total composition of the funds:
with a ratio of mass fractions of 1 part of the fipronil to 0.1-20 parts of the alphabethine.
2. The means according to claim 1, characterized in that it is a finished shape in the form of droplets for topical use and contains fipronil at a concentration of 2.5-10 wt.% And alphabipermethrin at a concentration of 0.25-2.5 wt.%.
3. The means according to claim 1, characterized in that it is a finished shape in the form of lotion, a solution or spray for applying to wool, skin, bird plumage and contains fipronil at a concentration of 0.05-1.0 wt.% And alphabipermetrin in Concentrations of 0.01-1.0 wt.% And further comprises repellents at a concentration of 5% by weight and more.
4. The means according to claim 1, characterized in that it is a finished shape in the form of a solution, lotion or emulsion for the processing of places of animal content and contains 0.05-1.0 wt.% Fipronil and 0.05-1.0 wt %. Alphazipermetrina.
5. A means according to any one of claims 2-4, characterized in that it additionally contains benzylbenzoate at a concentration of 0.1-1.0 wt.% And / or Extract of Melia (Melia Azedarach L.) at a concentration of 0.1-1, 0 wt.%.
6. The means according to claim 1, which is the finished shape of the air conditioner for wool in the form of a balsam or spray, characterized in that it contains fipronil at a concentration of 0.01-0.1 wt.%, Alphazipermetrin at a concentration of 0.01-0.1 wt.% and additionally may contain benzylbenzoate at a concentration of not more than 1 wt.% And Melia extract (Melia Azedarach L.) at a concentration of not more than 1 wt.%.
7. A means of claim 1, characterized in that it is a concentrate in a liquid form, which contains, wt.%:
8. A means of claim 1, characterized in that it is used as part of a collar of polymer, natural or combined materials.
Insectoacaricides.
Derativation means.
Plan.
1. General characteristics and classification of inhibitoacaricides.
2. Phosporganic connections.
3. Chlororganic compounds, carbamic acid derivatives.
4. Sulfur preparations.
5. Preparations of different chemical groups.
6. Derativational funds.
General characteristics and classification of insectoacaricides
Insectoacaricides - preparations of chemical or biological origin designed to combat harmful insects and ticks.
By origin, they are divided into: phosphorodorganic compounds, chlororganic compounds, carbamates, synthetic pyrethroids and preparations of different groups.
Of the total volume of spent insectoacaricides, the FOS accounts for 43%, HOS - 17%, carbamates -25%, of the other 15%.
Different arthropods, as well as intermediate forms of their development are not very sensitive to pharmacological agents. Therefore, in addition to the overall concept of insecticidal influence, the actions are distinguished:
ovocidal - the destruction of insect eggs,
larvicido - the destruction of larvae and caterpillars,
acaricido - destruction of ticks;
insecticidal - Destruction of insects.
Substances that scare insects from animals are called repellentsand funds attracting insects - atractants.
In the paths of penetration into the insect organism they are divided into:
Contact penetrating hemolyimph through insect cuticle;
Intestinal insecting insect through the digestive apparatus;
Fumigant, penetrating through the breathing apparatus.
In recent years, attention is paid to the insecticides of the system action. The animal enteral or parenterally entered into the organism in harmless doses for it, systemic insecticides are lichnic by the larvae migrating in the tissues of the animal.
Requirements for insectoacaricides:
1. Must have a specific effect on arthropods at all stages of development when using minimum doses;
2. maintain efficiency in various meteo conditions;
3. be economical;
4. Being safe (for service personnel and animals);
5. Do not have a remote effect effect.
Insecticides are used in natural conditions in places of cluster and insects, indoors and on the body of animals.
Apply them by spraying, pollinating, bathing of animals and aerosol processing.
Insectoacaricides are used in the form of solutions, emulsions, lotions, suspensions, powders (healing), aerosols, PUR-ONOV, insecticidal ointments, insecticidal pencils, insecticidal soaps, zooshampune, films, tags, collars, flue checkers.
The type of habitat of arthropods and the phase of ontogenesis determines the choice of means of struggle:
when combating sarkopotoid ticks - the pit and spraying of animals;
with gnus and blindness - aerosol processing and spraying;
with lshami and flea - insecticidal powders, shampoos, various soaps, etc.
- 2 - Phosphorian compounds (FOS)
The compounds of this group are esters of a row of acids: phosphoric, thiophosphoric, dithiophosphorus, etc.
The advantages of the FOS are a wide range of insecticidal action, low resistance in environmental objects.
FOS is excreted unchanged through the respiratory tract (20-25%), with urine (30%).
For FOS is characterized by the phenomenon of "lethal synthesis", when more toxic metabolites are formed from less toxic source preparations.
Chlorofos (Negulon, Diptext)Shlorophosum.
White crystalline powder, well soluble in water and most organic solvents.
Definitely acts on insects and helminths. Apply for processing animals against flying insects. Cows are treated after the boobs. It has high systemic activity. It kills the larvae of the hedges in the tissues of the animal, not only with internal, but also in external use.
Hydromemine chlorofos.Hypodermini-chlorophosum .
11.6% chlorophos alcohol solution.
Transparent yellowish color liquid with a slight aromatic smell. Apply against the larvae of the subcutaneous fusion by watering a cattle in a dose of 16 ml - animal weighing up to 200 kg and 24 ml - with a greater mass.
DDVF (Dichlorfos, Dichlofos)DDVF.
Transparent colorless or weakly yellow liquid, poorly soluble in water.
It has a selective effect on insects, ticks, helminths. It is part of the preparation "Estrosol".
Carbofos.Carbophosum.
Colorless liquid. Used in the form of 1% water emulsion and 4% of the dust, shampoo "Pedilin" - to combat eggs and larvae of lice, carbosol aerosol.
DiazinonDiazinonum (neocidol, Bazudin).
In the Republic of Belarus produced under the name "Racidol".
Cattle treatment is carried out in a 1: 1000, sheep and pigs ratio 1: 2400.
Colorless oily liquid, poorly soluble in water.
Released in the form of 25 - 60% of the emulsion concentrate, 40% wettable powder, 5% of the dryer.
Dursban, sulphidophos, foxime, trichloromethophos, phthalofos, etc. are also used.
ProteidProteidum
The drug contains 3% alpha cypermetrin and 30% chlorophenvinphos emulsifiers and organic solvents.
Before use, the drug is bred in a ratio of 1: 1000.
Rateid.Rateidum
Insectoacaricidal preparation, which is a transparent liquid of yellow or light brown with a specific smell. Contains 5% cypermethrin, 30% chlorophenvinfos, emulsifiers and organic solvents.
The protective residual effect on the skin and hair cover of animals is preserved up to 30 days.
Before use, raheid is mixed with water in a ratio of 1 part of the drug and 1000 parts of water (1: 1000).
Insects are such creatures that can adapt to any conditions. That is why they are at any point in the world. Unfortunately, together with his population, they distribute great amount Diseases for animals and people. Some of the viruses are deadly even in small quantities. Because of which it is impossible to ignore the problem. Pharmacist scientists have invented acaricides to combat insects.
Diseases and viruses in animals
The problem of pathogens exists no longer than a dozen years. Previously, it was treated with phosphoric and chlorine organic drugs. Unfortunately, they are very toxic and leave after themselves adverse effects. The most young and oldest individuals of animals were especially suffering, because their immunity is unable to deal with either insects or with side effects drugs.
What is dangerous contact with insects for people and animals:
Other insects can cause scabies, ear tick, itching tick.
Medical preparations
Today, syntactic insectoacharicidal drugs are used. They are safer for animals and people, but this is not the only one plus compared to the preceding acaricidal drugs from ticks and other insects:
- One insectoacaricidal agent is most often universally and helps to get rid of various insects.
- Chemicals are not able to get rid of eggs and insect larvae. Why often poison kills adult individuals, but the problem returns again, after a while. Modern drugs act much longer and prevent the emergence of new insects on the light, and the new tool in the insects themselves acts directly on the eggs.
- Security for people and animals counseling the minimum absorption effect.
The tool deployed on the four friend saves protective properties Until one month, which prevents infection when walking, contact with social reservoir or when communicating with patients with animals.
Communicated funds
Forms of release of drugs are completely different: collars, sprays, shampoos, drops. To the most popular liquid means relate:
Other forms of protection
The type of protective means depends on the size of the animal, mass and degree of infection. You can use special collars:
Whatever reviews about acaricides should not be engaged in self-medication. It is better to visit the veterinarian specialist and get accurate recommendationSince it may differ due to the type of animal, size and stages of the disease.
Insectoacaricides
In the complex of methods of combating arthropods, the use of various chemicals of natural or synthetic origin is important. At the same time, the means used against insects (insecticides) and against ticks (acaricides) are distinguished. Many drugs are used simultaneously to fight ticks and insects. In this regard, for the convenience of presenting and using the material, information about insecticides and acaricides consider it appropriate to put in one section.
It should be remembered that the absolute majority of injectacaricides can be extremely dangerous for animals and humans, so the treatment requires accuracy, clarity, punctuality, the correctness of the preparation of working solutions, compliance with the deadlines and doses of their application. Special attention should be appreciated by personal hygiene conditions. It is necessary to respect the timing of the use of milk and meat when using animal insectoacaricides. Permeter
For many years, the search for effective, affordable, harmless, cheap and ecologically safe tools The fight against arthropod-insects and ticks, many of which are dangerous to humans and cause significant damage to the national economy.
In the last 30-40 years, close attention was paid attention to natural pyrendines, and then on their synthetic analogues - Pyrethroids. The researchers they attracted high efficiency, low toxicity for mammals, rapid destruction and removal of warm-blooded organism. Pyrethroids have high lipophilicity, so quickly penetrate into vital bodies of arthropods. The activity of pyndroids significantly exceeds chlorine and phosphorodorganic compounds, as well as carbamic acid esters.
Permethrin containing a mixture of cis and transisomers in a 2: 3 ratio is an oily liquid with a weak odor, well soluble in organic solvents. Pyrethroids are poisons of neuro-paralytic action. It is known that the insecticidal activity of pyrethroids is enhanced with a decrease in temperature. The increased activity of metabolic processes in the body of insects at high temperatures contributes to a more rapid decay of drugs, thereby weakening their insecticidal action. Permetrin refers to moderately toxic compounds: LD50 it for rats 430-4000 mg / kg, for mice -540-2690 mg / kg.
Works on the study of permetrics against insects are numerous. This was the effectiveness of anometric-H (an analog permethrin, contains a mixture of trans- and oursisomers) against Hyalomma Plumbeum ticks. In 0.1% concentration, this drug protected cattle for 3 ... 4 days. Similar effectiveness was obtained and when applying 0.05% concentrations of the drug.
Mechanical Aerosols permember, used at a dose of 2 mg d.V. / m, effective against flies. Regular processing carried out once a week allow you to maintain the number of flies at a much low level. During the processes and the 30-minute exposure in the air, the permererin concentration is created, equal to 0.6 mg / m, which is 5 times lower than the shoe (3 mg / m). In the specified dose of aerosols of this drug is not toxic for animals, and the residual quantities were found only in skin samples.
For systematic use against Gnus, permethrin is recommended at a dose of 0.250 g per one adult animal and 0.125 g by treating young by the mid-paying spraying by 0.05% aqueous emulsion, respectively, 500 and 250 ml, respectively, and low-pass spraying 0.25% emulsion 100 and 50 ml per animal.
Increasing doses when treating calves 10 times did not cause substantial deviations from them from physiological indicators.
The high insecticidal activity of the permererin preparations against the blinders and flies was established, the rational modes of their use for cattle treatments against gnus were determined.
Systematic as necessary, low-volume spraying of 0.25% emulsion or medium-wide spraying 0.05% emulsion of these drugs with the help of the SGRU provide effective protection against the gnus, prevent the average daily impact of the same cow at 0.850-1,750 l.
In these modes, permethrin is non-toxic, does not accumulate in the body and does not stand out with milk. Proteid is a drug produced by Cyanamide, USA. This is an inhibitoacaricide on a microemulsion basis containing 3% alphabipermetrin and 30% chlorophenvinfos with a synergistic effect. 20-fold overdose of the drug do not cause toxic phenomena in animals. It is allowed to use milk to eat 6 hours after processing livestock, slaughter on meat - after 7 days.
The preparation has a prolonged action, i.e. Protects animals within 42-56 days from scabies, for 12 weeks - from ixodic ticks. High lipophilicity provides long-term preservation of the drug on the skin. Proteid has strong repellent properties. The drug has low toxicity. It is active in relation to eggs, larval and adult forms of scaffold ticks, various types of flies and lice of ruminants. The processing of animals is carried out at an air temperature not lower than 180 ° C 0.1% proteid concentration at the calculation of the flow rate of the working emulsion on one head 5-10 liters. Atmospheric precipitates do not affect the duration of the drug after animal processing. With the appearance of signs of poisoning in animals, atropine sulfate is used. Personal prevention should be observed.
Mustang is an aqueous emulsion containing 10% of zetacyiperin pyrethroid. In contrast to other analogues of cypermethrin, Mustang has 2 times more cis and transisomers, which determine the biological activity of the drug. Releases Mustang Fisci Corporation, USA.
Studies have shown that LD50 for white mice was 315 mg / kg, which refers it to the third class of danger. CC50 for Lricimis amounted to 0.0000058%.
When processed by the drug of cows at a concentration of 0.0124% (which is an order of magnitude higher than recommended), all the ixodic ticks died, and the drug did not detect in milk. After processing slaughter, animals can be made in 12 days.
Based on the studies, the effective dose of Mustang-0.3 ml per animal or 0.006% of the aqueous emulsion was determined during the spraying of cows at the rate of 0.5 liters per animal.
Comparing the cost of consumption on one animal Mustang with widely known drugs - Bloat, Butoxies and Tsimbush, it was found that 1 liter of Mustanga can be treated with 3.3 thousand kits, a fleet - 130 goals, butoxy - 660 goal, Cimbush - 660 goal. , cost 1 l Mustang $ 24.0; Blood - $ 27.5; Butoxes - $ 25.0; Cimbush - $ 25.5; The cost of diazine is twice as high.
The active substance is ectomine is cis-isomer-containing cypermethrine, synthetic pyrethroid. Derivatives from natural pyrethroids, synthetic preparations belong to the most modern class of insecticides and acaricides.
Empirical formula Extortin C22H19S2O3, molecular weight 416.3. The drug is a viscous yellow-brown semi-liquid mass with a melting point of 30-600C. The dissolution level in water is about 1: 100000, it also dissolves in most organic solvents.
When studying acute toxicity for rats, the LD50 is in Extortin-100 K.E. 1108 mg / kg (acute oral) and more than 2000 mg / kg (sharp dermal).
Active ingredient and 10% ectomine emulsion concentrate are small-toxic for mammals. The active substance is insignificantly annoying the skin, the minimum - the eyes of rabbits. The drug is practically non-toxic for birds, but highly toxic for fish and bees. It is characterized by a quick metabolization and removal from the body of animals, as well as a quick decay.
Extortin can be prescribed a large and small cattle, pigs, a bird and apply for the processing of livestock premises. It is effective against ixodic ticks, with scabies, is shown when dealing with flies, lice, sheep plants, larvae of the subcutaneous oath.
Called cattle for irrigation of the body surface and for bathing in Baths EXTOMIN-100 K.E. Used in 0.1% concentration, for spraying the body along the ridge - 0.5% concentration.
Sheeps and pigs for spraying the body and bathing in the baths The drug is used in 0.1% concentration, and for spraying the bird - 0.1-0.2% concentration.
When processing animal breeding premises, ectomin is used in 1 -2% concentration.
3 days before the slaughter of animals, they should not be treated with ectomine. When applying the drug, milk can be used for food purposes.
Extopor is a small substance, does not irritate the skin of animals, but irritates the eyes of rabbits. Cypermethrin with a high content of cis-isomers is almost non-toxic for birds, but toxic for fish and bees. For ectopore, LD50 for rats (oral oral and sharp dermal) is more than 2000 mg / kg.
The finished ectopor is applied to the surface of the skin of the back of animals in the form of a jet directly from the vials, while the sprayers or baths are not needed. The dose of ectopor for ruminants is 1 ml per 5 kg of live weight. Slaughter of animals after applying the ectopora is allowed after 3 days. When working with ectopor, it is necessary to observe personal prevention measures.
Neocidol
Neocytol (diazine) refers to phosphorodorganic compounds with an empirical formula D ^ H ^^ O ^ s and a molecular weight of 304.35. The active substance is Diazinon. This is a yellow-brown liquid with a boiling point of 840С and solubility in water at 200 ° C. 40 mg / l.
LD50 for white rats neosidol-600 k.e. Under oral administration is 1053 mg / kg, when applied to the skin - more than 3100 mg / kg. The drug is toxic for bees, birds and some species of fish. Cattle tolerates a dose of 16 mg / kg of living mass without toxic symptoms, sheep - 20 mg / kg, pigs do not have the symptoms of toxicosis in one-time treatment with 0.25% drug or three-time treatment with an interval of 7 days 0.005% neosidol.
For spraying cattle neocidal-600 k.e. It is used in 0.1% concentration, pigs - 0.04%. For swimming sheep, a drug is used in 0.042% concentration, and cattle - in 0.01%.
For disinvasia livestock premises neocidal-600 K.E. Take in 4% concentration at the rate of 5 liters of 100 sq. M. Square.
The drug has a high degree of biorescape, the half-life of it in the soil of 1 -4 weeks depending on climatic and other conditions. Unlike chlororganic compounds, neocidal is not accumulated in the food chain. It is adsorbed in the soil, so it is not washed into groundwater.
Animals are treated with neocyedol 14 days before slaughter. Milk for food purposes can be used 3 days after processing. When working with nonocyidol, personal prevention measures should be observed.
Butoxy (deltamerin) refers to a group of synthetic pyrethroids with empirical formulas C22 H19 VG2 N O3 and a molecular weight of 505.2. Melting point 98-1010 C. Like other synthetic pyrethroids, butoxy dissolves in mineral and vegetable oils and is practically not dissolved in water. In this regard, when it is introduced into the organism in oil solutions, it is toxic, and when aqueous suspension is used non-toxic. For example, with oral administration of it with white rats, in the form of oil solutions, LD50 is 135 mg / kg, and when an aqueous suspension is introduced - more than 5000 mg / kg.
Butoxies are effective against the ixodic and scaffold ticks, lice, flies, bursts and other animals spray the suspension of the drug, you can bathe in the baths, spray the butoxy powder.
Anti-water ticks of animals are treated with butoxy in 0.0025% concentration. Anti-potholes are applied against the preparation of prevention once in 0.003% concentration, and the treated animal treatment with butoxes is carried out with a 0.005% drug twice with an interval of 810 days. Against lice, flies and other insects, butoxy are applied in 0.0025% concentration. In case of animals, the efficiency of the drug is not reduced to rain.
Slaughter animals on meat and milk consumption is allowed immediately after applying butoxes. When working with the drug, personal prevention measures should be observed.
Stomozan
Alfakron
Alfacron-10 is a wetting powder containing 10% of the azamethyphos related to the organophosphate group. It is easily and quickly metabolized for mammals, easily and quickly and is hydrolyzed in water. The preparation is toxic for bees and fish.
For spraying 500 g of alphaacron-10, it is thoroughly mixed with 4 liters of warm water and treated against flies 100 m2 outdoor or 200 m 2 wall surface.
For fading, they take 250 g of alphaacron-10 and mix with 250 ml of water. Processing about 2% of the surface for every 100 m 2 floor or 200 m wall surface. Preparations are applied on the day of preparation. Antidote is atropine. When working with Alfakron-10, it is necessary to respect personal prevention measures.
Tiffol-300 K.E. Contains 30% of tsimiazole (amidine) in the form of an emulsifying concentrate. The drug is used to deal with ixodic ticks and lice in cattle and horses in 0.1% concentration. Treatments are subjected to animals over 4 weeks of age, except for patients and weakened. Animal treatment with Tiffatol is well tolerated.
After processing animals by Typatol slaughter, they are allowed after 3 days, milk is used without restrictions. It should be avoided by the way of the human skin.
Nobores
Nepacity of VRG-2 (water-soluble granulate) contains 2% of the cyrozazine, which is derived triazine.
Lackless inhibits the growth of the larvae flies in liquid dung and in fermenting feed residues. The drug can be used in the form of a powder or aqueous solution.
When disinfection of the area of \u200b\u200bpremises, where the calves and young cattle are contained on fattening, there are three coat processing with an interval of 14 days. It is better to process the floor surface along the walls, where the breakdown of flies usually passes. For this, 250 g of granulate is used to process a strip 20 m long and 50 cm wide.
In the room where pigs are contained, there are two treatments with an interval of 14 days. For this, 250 g of granulate is necessary for processing 10 m 2 of the floor area (slit or perforated gear) or 20 g of powder dissolved in water for processing 20 m 2 outdoor area. It should be avoided to hit the eyes, on the skin and clothing, observe general rules personal security.
Cyperyl - an insectoacaricidal drug, the current principle of which is cypermethrine (RS) -3-phenoxybenzyl (IRS ^ iPK;, trans-3- (2,2-dichloro-vinyl) -2,2-dimethylcyclopropan carboxylate.
Cyperil - yellowish color liquid with an aromatic smell, containing 5% cypermethrin, well emulsifying in water.
Tsiperil has wide spectrum Actions on insects and ticks causes their paralysis, and then death. For warm-blooded drug, medium-stage: LD50 for rats of the current start of the cyager with oral administration - 251 mg / kg, when applied to the skin - 1600 mg / kg, LD50 of the cyager itself - compliance with 2080 mg / kg and 2000 mg / kg body weight. Dosage and application
Cattle. No daisy cattle for protection against Ixodic ticks spray 0.005-0,0125% by the emulsions of the drug to the complete wetting of the skin and hair cover once every 7-10 days, against the psoropotosis - on the interval of 10-12 days. Slaughter animals on meat is allowed 15 days after the last processing. With a forced kill animals, the meat is previously used on animal feeds or other animal species.
Cows and young cattle against flies against flies and field flies, carriers of causisiosis pathogens, spray 0.0125% of cyzryl emulsion with a flow rate of 20-50 ml per animal, inflicting the preparation surface to the back area and head. The first spraying is carried out shortly after the start of the pasture season, then the processing is repeated 2 times with an interval of 3 weeks.
To protect against the benus (mosquitoes, flies, blind, midges, hoarses), animals spray 0.0125% emulsion with an interval of 2-3 days, and with high numbers of insects daily before pasture for pasture with a flow rate of 250-500 ml. Milk from treated cows is used without restrictions, the period of slaughter of animals is not regulated.
Sheep against psuoptosis, sheep runs and lice thoroughly spray or bathe in 0.005% water emulsion cyzryl twice with an interval of 10-12 days. Downtown Baths spend 0.0075% emulsion. Slaughter animals on meat is allowed in 15 days. With the slaughter of this period of this period, the meat is used on animals or other animal species.
Poultry houses against chicken ticks, bugs, flies spray 0.0125% emulsion of the drug with a flow rate of 100-200 ml / m2 after removing the bird's premises.
Pigs and horses against sarcoptosis and lice spray 0.0125% cyager emulsion twice with an interval of 10-12 days. Slaughter animals on meat is allowed in 10 days.
Dogs, cats, sands, foxes, other carnivorous against causative agents of scales, demodecosis, fleas, lice, ixodic ticks spray
0.0125% aqueous water emulsion to full wetting of the affected areas or the entire leather-hair. Re-processing is carried out in 8-10 days.
For disinsection of premises against room and other types of flies, fleas and mosquitoes, 0.0125% aqueous water emulsion with a flow rate of 100-200 ml / m2 by spraying is used.
Against flies selectively irrigate the places of their landings, as well as the outer walls of the buildings, garbage collectors and navigation. Repeated processing is carried out as insects are increasing.
Against cockroaches selectively process their habitats, possible paths Movement and shelter (slots in walls, ventilation holes, surfaces behind heating devices, etc.) 0.1% of the drug emulsion.
To destroy fleas spray walls on a height of 1 m and the floor.
To destroy mosquitoes selectively spray the places of their cluster (walls, ceilings, window Rama), as well as external walls of buildings. The mosquito larvae in the reservoirs of a non-breeding value, in the basements of buildings and structures, destroy 0.0125% emulsion to the aqueous surface in the amount of 100 ml / m2.
When preparing an aqueous emulsion, the treasury of cypreier is mixed with a small amount of water (1: 3) and, with a thorough stirring, add to a bath or a spraying container with measured water.
Workers emulsions are prepared immediately before applying in accordance with the instruction.
Forms of release and storage conditions. Available in glass and polyethylene bottles with a capacity of 0.06-0.5-1 l and polyethylene canices of 2-5-10 liters. Stored Tsiperil in a closed factory packaging, away from heat sources and open flames at a temperature not higher than 300c in a non-residential room, inaccessible to unauthorized persons, under the lock. Transport Tsiperil to any type of transport in compliance with the existing rules.
Shelf life. Warranty period Storage - 2 years. Produced by Narvak (Moscow).
Acaircutin
This is a colorless transparent liquid with a weak odor, which is a solution of ivermectin in organic solvents.
Dosage and application.
With ear scabies of dogs and cats, acaomejects are applied from a spray bottle to the inner surface of the auricle in an amount of 1 -2.5 ml, providing uniform wetting of the skin and crusts.
In case of sarcoptosis and democosa, dogs, notooderosis of cats and dogs are wetted by ticks and neighboring parts of the body.
Against lice, valvelas and flea, acaomejectin is applied in small areas to the outer surface of the ears, the head, neck, back. Anti-flea simultaneously conduct disinsection insecticide bedding, gender and other deposits.
Release form and storage. Acaircutin is produced in polyethylene bottles with a capacity of 25 ml with an aerosol sprayer.
Acaircutin stores in a closed factory package, away from heat sources, open flame, in a dry room at a temperature not higher than 300 s under the lock (List B).
Oodctin
Dosage and application. Odectin is used by dogs, cats, foxams, foxes, other carnivorous, sick ear scabies, sarcoptosis, notoodecara, demodicosis, nematodosa (Toxocara Canis, Toxocara LEONINA, Ancilostoma Caninum, Uncinaria Stenocephala), as well as affected by lshami, fleas and valvened.
The drug is administered under the scope of the forearm or behind the shoulder situation in compliance with the aseptic rules from a sypress with a short needle (1.5-2.0 cm) at a dose of 0.2 ml / kg (200 μg / kg D.V.) body weight .
Anti-demodecosis can be used in conjunction with the cavity means of therapy, against fleas simultaneously conduct disinsection of the litter, gender and other insecticide facilities allowed for these purposes.
Release form. Oodkentine is produced in the form of a sterile 0.1% solution in glass or polyethylene bottles with a capacity of 1 -20 ml or ampoules of 1-5 ml.
Storage conditions. Store the otodctin in a closed factory package, away from heat sources, open flame, in a dry room at a temperature not higher than 300 s (list B).
Shelf life. The warranty expiration date is 5 years from the date of manufacture. Produced by Narvak (Moscow).
Injection hypodetectin
Hydrancytin injection - a solution of 22,23-dihydro-servmectin B1 in organic solvents. Ready for use The preparation in the form of a colorless transparent liquid with a weak odor.
Biological properties.
In doses used in hypodermatosis, non-toxic for cattle.
Dosage and application.
The drug is administered subcutaneously in the region of the lower third of the neck with adult animals in a dose of 2 ml, young weighing up to 200 kg - 1 ml.
For the purpose of early chemotherapy, the processing of the entire herd is carried out in the fall in September, October, November.
In the spring (in March), with the appearance of the first fiscaset capsules (gaps), depending on the extensiveness of the lesion, all the livestock or only affected animal larvae are treated.
Slaughter animals on meat is allowed no earlier than 5 days after the use of the drug.
Release form and storage conditions.
Injection hypodectal is released in glass bottles of 10-500 ml. Transport by any type of transport in compliance with the existing rules. It is not allowed to transport the drug in conjunction with food and feed. Keeping the hypodetectin injecting in a closed factory packaging in a dark room, away from heat sources and open flames under the lock (B) at a temperature not higher than 300 C.
Shelf life. 5 years from the date of manufacture. Produced by Narvak (Moscow).
Preparation Akrodex
The Acreex preparation is used in demodecosis and animal scabies. We produce it in aerosol cylinders with a capacity of 385 ml or in the amazing cylinders "Rosink" (one spray head and four 500 ml containers are included in the kit). The preparation is stored at a temperature of 5-20 ° C. The shelf life of the drug is 1 year.
The drug Achrudex in the form of an aerosol is applied to the whole skin covering Animal from a distance of 20-30 cm for 25-30 s.
During demodicosis, the drug is used fourfold with an interval of 5-7 days, with a psoroptosis-twice with an interval of 8-12 days. From one 385 ml spray with a volume of 385 ml, 5-6 heads of adult cattle, from the spray "Rosinka" - 7-8 heads. The Achrodex drug can not be sprayed near open fire, overheating the cans with the preparation above 50 ° C. When working with the Acreex preparation, you need to use a gauze bandage or respirator. At this time, it is impossible to smoke and eat. At the end of the work, wash your hands with warm water with soap.
Dermatosol
The drug Dermatosol in the amusemental cannons "Rosinka" is used in the demodicosis and scabies of animals. The complex consists of a spray head and four hermetically closed containers of 500 ml. The shelf life of the drug is 1 year.
The dermatosol is treated with the entire surface of the animal body from a distance of 20-30 cm for 25-30 s.
During demodicosis, the drug dermatosol is used fourfold with an interval of 5-7 days, with a mixture-twice-twice interval 8-10 days. One capacitance of the drug is sufficient for processing 7-8 heads of adult cattle.
When working with the drug, dermatosol should be remembered that it can not be sprayed near open fire, heated it over 50 ° C. Respiratory organs need to close with a gauze bandage or respirator. During working with the drug, it is impossible to eat and smoke. After completing the work, be sure to wash your hands with warm water with soap.
Aerol-2 is a homogeneous movable liquid of dark-crying color, with water forms a resistant emulsion. Shelf life in closed container - 1.5 years.
In the form of thermomechanical aerosols, the drug is used to combat flies and ixodic ticks in rooms. Aerol-2 is highly toxic for humans and animals, so when working with the drug observe special precautions. Thermomechanical aerosols are obtained using the AG-UD-2 generator. In the absence of a bird, the treatment of poultry houses are carried out by aerosols at the rate of 20 ml of the drug per 1 m room double when each processing of 24 hours is exposed. The first processing is carried out before mechanical cleaning, the second - after it. After treatments, the poultry houses are ventilated for 6 hours.
Similarly, the rooms for cattle against xexodic ticks are treated. After carrying out the premises of the drinking bowl and the feeders wash warm water.
Working with the generator is allowed workers familiar with the instructions for using it, subject to all security rules.
Chlorofos.
Chlorofos (dipterex) - white crystalline powder dissolves in water (24.2% at 35 °) and many organic solvents. In an alkaline medium, chlorophos is hydrolyzed to form a high-precance compound DDVF (dimethyl-dichloro vinyl phosphate).
Chlorofos is produced in the form of 97% pure or 80% technical preparations, 50 and 80% wetting powders, etc.
The drug of medium-toxic action is effective both inhibitoacaricide and anthelminty. The drug oppresses cholinesterase.
Chlorofos is used for hypodermatosis by rubbing it into the skin of the animal back in the form of 4% (for the ADV) solution at a dose of 200-250 ml per animal. In addition, hypodermatosis applies a hypodermine-chlorofos 11.6%-single-alcohol solution of chlorofos.
With sarcoptosis of pigs, 1 -2% solutions of chlorofos are used, with psuoptosis of ruminants and to combat ixodic ticks - 1% solution.
In case of poisoning, the best antidot is considered atropine at a dose for cattle 1 ml per 100 kg of alive mass in the form of a 1% solution, sheep - 0.5-1 ml on the head. If necessary, the administration of atropine is repeated after 1-2 h in similar doses.
In order to avoid the formation of DDVF, it is impossible to overheat the chlorofos solutions above 50 ° C, as well as its contacts with alkalis.
Slaughter animals on meat after processing chlorophos is allowed after 21 days. When working with the drug complies with precautions.
Ingredients: 100 ml of inhumon contains 10 g of the active substance of the substance.
Negulon is designed to combat migrating larvae subcutaneous heaps.
Inhumon-solution n is a finished solution that is applied once with a dosing device with a thin jet along the spine on the back of the animal at the rate of the calculation:
In order to prevent animal hypodermatosis, it should be processed in the fall, after the end of the summer of the hedge. If the treatment did not take place in the fall, it must be carried out against the larvae of the second and third stage in the spring.
It should not be treated with animals from December to March, since at this time the larvae of the hedge migrates in the spinal channel and when they destroy them there may be paralysis.
Slaughter animals on meat is allowed no earlier than a day after processing. Milk from processed cows is used without restrictions (recommendations of the company "Bayer AG").
Other cholinesterase inhibitors should not be applied, phenothiazine preparations and muscle relaxants 10 days before and within 10 days after applying thereof.
In the case of severe intoxication, for example, strong convulsions, ataxia, shortness of breath, loss of consciousness, should be used as an antidote 1% solution of atropine sulfate intravenously or intramuscularly in a dose for cattle - 2.5 ml per 100 kg of alive mass.
Plots of the body that came into contact with the drug should be carefully flushed.
Packaging: Blocked with a capacity of 1000 ml. Releases drug "Bayer AG", Germany.
Benzophosphate
The active beginning of the benzophosphate is 0.0-diethyl ^ (6-chloro benzoxazolinyl-z-methyl) -dithophosphate. This is a white crystalline substance with a melting point of 45-47 ° C, poorly dissolved in water. The drug is produced in the form of a 30% emulsifying concentrate, shelf life - 2 years.
Benzophosphate is medium-tooth for warm-blooded animals. It has high acaricidal, insecticidal and oocidal properties.
To combat ashode ticks of cattle, benzophosphate is used by spraying it once a week with a 0.2% emulsion at a flow rate of 2-4 liters per animal. For bathing of cattle, 0.15% emulsion, sheep - 0.2% emulsion are used.
In the indoors of the ixode ticks, they are destroyed by spraying with a 0.2% emulsion of the drug at the rate of 200 ml / m2 of the surface. The processing of lactating cows with benzophosphate is not allowed. Slaughter of animals on the meat is allowed to spend 40 days after the last treatment with benzophosphate.
Poultry houses (without birds) are treated with a 0.25% emulsion of benzophosphate at a temperature of 25 ° C per 100-200 ml / m2 surface. In the case of the appearance of intoxication in animals, an intramuscularly used 1% solution of atropine sulfate sulfate with a large cattle 1 ml per 100 kg of alive mass, sheep-0.5-1 ml on the head.
When working with benzophosphate should be used individual means protection.
Carbofos.
Carbofos (VETIOL) - the beginning of 0.0-dimethyl ^ - (1,2-bis-dicarboeteethyl) -dithofos. It is an oily liquid, poorly dissolved in water. The drug is produced in the form of 30-40 or 50% concentrate.
Shelf life - 2 years.
For warm-blooded animals, carbofos medium-toxic, has cumulative properties, lingering in the body of animals to 10-12 days. The drug is used against flies, bugs, scabies and other ticks. In case of scabies of sheep in baths with a 0.25% water emulsion, a single prophylactic checkout and two-time healing was organized with an interval of 10 days. The slaughter of sheep on the meat is allowed 5 days after processing. A 0.25-0.5% carbofos concentration was used to treat poultry houses against ticks at the rate of 150200 ml of emulsion per 1 m2 surface.
In the poisoning of animals, they introduce a 1% solution of atropine intramuscularly 0.5 ml per head.
When working with carboofos, you follow the necessary safety rules, use individual means of protection.
Dichlorofos.
Dichlorofos (DDVF, Brenet, Chlorvinfos) in a chemical ratio represents 0.0-dimethyl-0,2-dichloro vinyl phosphate. It is a colorless or yellowish liquid, has an unpleasant smell, poorly dissolved in water. The drug is produced in the form of a 50% emulsifying concentrate or 80% technical drug. Shelf life - 2 years.
The drug is used in the form of aerosols in pigsties in the presence of animals (except for artificial insemination and sumps with newborn piglets). For this, generators ag-UD-2 are used. The temperature in the premises should be 18-19 ° C. The drug is used in the form of a 1% aqueous emulsion at the rate of 2 ml / m3 at a cost of emulsion of 1.25 liters per minute and speed of operation of 3000 rpm. After processing, it is withstanding the exposition of 30 minutes, the premises are ventilated.
In the absence of equipment in the rooms at the rate of each 1000 m3, there are containers in a checker order, in each of which 1 kg of chlorofos and 1 kg of caustic sodium are added, 1 liters of water are added and stirred. The operator must escape from the room. Disinfection exposure lasts 30 minutes. After that, the premises are ventilated.
The drug is used to treat cattle against gnus. To do this, the pasture uses a 0.5% emulsion at the rate of 500 ml of the drug on an adult animal and 300 ml - on one head of young.
Slaughter on animal meat is allowed 3 days after the last processing. As an antidote, 1% atropine sulfate was used if necessary at the rate of 0.5 ml per 100 kg of alive mass. When working with the drug, personal safety measures should be observed.
Dykresil
In a chemical ratio, it is a dijon-op-methyl carbamic acid. White crystalline substance insoluble in water. Available in the form of a 30% emulsifying concentrate, 40% powder or 7% dryer. The drug is medium-toxic for warm-blooded animals. The shelf life of the concentrate and the dryer - 2 years, the powder is 1 year.
Catted cattle struck by garlic or ixodic ticks is treated with 0.75% dijer emulsion at the rate of 3 liters per each animal. Anti-water ticks are treated once every 6 days.
A 0.5% emulsion of the drug is used for scabies for scabies, 1% emulsion is used to deacarize the premises. In case of sarcoptosis, pigs are treated twice with 0.5% aqueous emulsion at the rate of 1-2 liters per animal with an interval of 8-10 days.
Slaughter of livestock is allowed to meat through 7, pigs - 10 days after the last processing. When working with DiCresil, it is necessary to follow personal safety measures.
In chemical terms - 0.0-diethyl-0,3,5,5-three-chloropyridyl phosphate. This is a white crystalline substance, poorly dissolved in water. The preparation is produced in the form of 12% -, 40.8% -, 25% concentrates, 25% -, 40.8% of 50% oil solutions, as well as 1% - or 10% granules . Dursban storage period is 1 year.
Sheep baths in bathtubs with pszoptosis using 0.1% Dursban emulsion once every 10 days twice. The lactating cattle does not proceed.
The slaughter of cattle is allowed in 20 days, and sheep - 30 days after the last processing of their Dursban. When working with the drug apply individual means of protection.
The current beginning of Sebatilation (Velson) is 0.0-diethyl-thiophosphoril-a-ox-imino-phenyl-sodium acetic acid. This is a brown oily liquid, weakly dissolve in water. Shelf life - 2 years. Released in the form of 50% concentrate.
The drug is small toxic for animals. It is used in the pszoptosis of sheep in the form of water emulsions with a content of 0.05-0.1% ADV. Sheep baths once with the aim of preventing psuoptosis in a 0.05% emulsion, twice-after 10 days in the 0.1% emulsion of Sebazil.
In case of psuoptosis, cattle is treated with a 0.1% sebatile emulsion twice after 10 days at a temperature in rooms not lower than 10 ° C. The same concentration of the drug is treated with rooms at the rate of 400 ml / m2 area.
After processing Sebatal, the slaughter of sheep on the meat is allowed in 25 days, cattle - after 22 days.
In the poisoning of animals, 1% atropine sulfate is administered intramuscularly at a dose of 2 ml / 100 kg of vibrant mass.
When working with the drug, security measures must be followed.
Insektol.
The inset of the insektol is a pyrethroid resection. This white crystalline powder is practically dissolved in water. The drug is produced in unpaired cylinders of 450 g each or in aerosol packaging on 170 g. The shelf life of the drug is 1 year. The drug should be stored away from fire and feed, in the shade, at a temperature of from 5 to 25 ° C.
Insektol is small toxic for warm-blooded animals. It is used for processing against insects and ticks of milk acceptor points, Kormokuhogo, sanitary warro, warehouses. Apply the drug in the premises where there are no animals and in which there are no products. One cylinder weighing 170 g is sufficient for processing 1 m3 of the room. The exposure after treatment is withstanding 1.5 hours, then the premises are ventilated.
When working with the Insertol, use personal protective equipment.
Stomoxin
Stomoxin is the commercial name of drugs produced by the English company "Shepsoshe" using pyreteroid insecticide permethrin.
Stomoxin contains 25% of the cysisomera and 75% of the permeter transisomer, which ensures its safe use for animals, as well as for the processing of the premises.
The drug is produced in the form of an accessory powder containing 25% permemerin, which is applied to the surface of the premises to combat flies. For the same purpose, a cattle processing can be treated with oil containing 20% \u200b\u200bpermeter or a turpentine balsam preparation. It includes 0.1% permethrin, ensuring that healing wounds and abrasion on animals are in addition to fighting flies.