A common practice is to prescribe the drug "Curantil" to expectant mothers, as well as to women who are planning a pregnancy in the near future. So don't be surprised if your doctor writes you a prescription. How to take it, what is it for and is it not dangerous to use it? All these questions arise for a woman, and not always the local doctor, due to his workload, can answer them. Many mothers are surprised by the appointment of an "extra" drug, because it is believed that the fewer tablets, the healthier the baby will be. However, doctors have a different opinion, the side effects of "Curantil" are too insignificant and in most cases do not compare with the intended benefits for the mother and child.
When planning
Not every woman is prescribed a drug at this stage. Most often, you can talk about planning a pregnancy when a woman has certain health problems. If there was a history of miscarriages or abortions, infertility therapy, all this leads to the woman receiving treatment, and one of the components is Curantil. Side effects are minimal, so doctors sometimes even prescribe it "just in case." To understand what it is for, let's look at the pharmacological properties of the drug.
Influence on the body
"Curantil" is a drug that improves blood microcirculation. That is, we are not talking about large arteries and vessels, but about a network of small capillaries. They are the ones that go to every cell of our body, nourishing them and saturating them with oxygen. According to the mechanism of action, it is an antiplatelet agent that prevents cells from sticking together, resulting in blood clots.
For the expectant mother, this effect is very important, especially if she has a tendency to thrombus formation. Therefore, the doctor prescribes "Curantil". This method in most cases avoids complications from the internal organs. It happens that blockage of blood vessels leads to temporary infertility. In this case, against the background of treatment, a long-awaited conception may occur. Side effects of "Kurantila" can occur if there is anemia in the anamnesis, that is, the blood is already liquid.
Immunomodulator
This term is clearer. This means that the drug restores immunity. This happens because the drug is able to stimulate the synthesis of interferon. It is a special blood protein. The side effects of "Kurantil" continue to be carefully studied even today, because the mechanism of action of interferon has been clarified only in general terms. It is supposed to be safe for both mother and baby. But let's not forget that suppression of immunity is a physiological process aimed at reducing the risk of fetal rejection.
Creation of favorable conditions for conception
If a woman has already been examined with suspicion of infertility, then she knows very well what is at stake. Side effects of "Curantil" may not be taken into account, because it allows you to build up the endometrium in the uterine cavity. This is nothing more than the inner nutrient layer to which the ovum is attached. If a fertilized egg has descended into the uterus, and the endometrium is too thin, it will not be able to gain a foothold and a miscarriage will occur. A woman may not feel anything besides the usual menstruation. By the way, the latter is just a consequence of endometrial detachment. If the pregnancy has not occurred, then it becomes unnecessary. And after menstruation, a new cycle begins, and the nourishing layer of the endometrium inside the uterus grows again to receive the fertilized egg.
We deviated a little from the topic. So, doctors prescribe "Curantil" in order to build up the layer of the endometrium, considering it a good help for future conception. Alas, this fact has not yet been proven. Maybe it's just a matter of time. That is, perhaps the drug will not harm, but not the fact that it will provide the necessary assistance.
Prevention and treatment of varicose veins
This is another medical condition that should be kept under control if pregnancy is planned. "Curantil" helps to avoid thrombus formation, which can be a very significant help. Throughout all nine months, it is the vessels that are subjected to tremendous stress. For some women, signs of varicose veins are observed for the first time, while for others, existing problems are aggravated. Therefore, it will be very useful to undergo preventive and therapeutic courses before pregnancy. But if for a healthy person this drug will be an excellent help, then in the presence of certain diseases it is best to refuse it. It can also cause side effects, which we'll talk about now.
First trimester
At this time, women usually come to register at the antenatal clinic. And they immediately get a recommendation to drink "Curantil". Side effects during pregnancy are rarely discussed with women, and now the doctor does not even have a complete picture of their state of health. Therefore, it is best to postpone taking the drug until the test results are ready, and once again ask the doctor about its use.
Indeed, this drug is not a vitamin, and it should not be used for prophylaxis. In the first trimester, it is prescribed to improve uteroplacental blood flow, but the load on the vessels of these organs is still low. But if a woman's coagulogram shows a strong increased blood coagulation ability, then the appointment is justified.
The second point is the support of immunity, which is very important during this period. However, the effectiveness of interferon is questionable, so there are authoritative opinions that it is better to eat onions and garlic, fruits and vegetables, and also undergo hardening procedures. In many Western countries, doctors today refuse to prescribe Curantil to their patients. Side effects during early pregnancy depend on the individual characteristics of the body, but in some cases, the drug can cause bleeding.
Second part of pregnancy
Starting from the 20th week, the mother's body changes greatly. The load on all organs and systems is increasing, right now doctors most often prescribe "Curantil". The instruction describes side effects in some detail, now let's come to this. But can the benefit outweigh the perceived harm? During this period, you need to be very careful about the state of the vessels of the uterus and placenta. The baby is already almost formed, the mother's body is used to stress, but the vessels begin to feel an increased stress from the fetus, which needs more nutrients and oxygen.
If there is a risk of thrombosis of the placental and uterine arteries, then you need to regularly monitor the test indicators. Of great importance is the lumen of the vessels and the speed with which blood flows through the arteries from the placenta to the child. In any case, check with your doctor why he is prescribing this drug and whether it will harm your baby.
Third trimester
At later stages, the drug is recommended to be taken with placental insufficiency. This is especially true for complicated pregnancy. The drug helps to prevent aging of the placenta and significantly alleviates the condition. In addition, at a later date, the use of the drug can prevent the development of hypoxia in the fetus, improve its cerebral circulation, and help in the formation of the respiratory system. At this stage, blood supply plays a critical role for the fetus. And Kurantil helps to improve it significantly. He has quite a few contraindications, despite the good effect. Therefore, the doctor must carefully weigh the benefits and harms.
Starting from 33 weeks, many women are faced with "hiccupping" crumbs. For this physiological effect, it is customary to consider the rhythmic twitching of the abdomen, caused by short, light contractions of the uterus. One of the versions of this phenomenon is a lack of oxygen in the baby's body. If this is repeated over and over again, then "Courantil" is appointed.
Responsible for yourself
Despite the fact that it is prescribed as a vitamin, the drug is not such. Therefore, before purchasing it in a pharmacy, it is worth examining the side effects of "Curantila" during pregnancy. Reviews suggest that many moms experienced varying degrees of discomfort when taking it. This should be at least alarming.
It should be understood that the doctor does not remember by heart the entire list of contraindications, as well as the history of each patient. If a woman has been diagnosed with an acute heart attack or collapse, stenosis, then Curantil should not be included in the course of treatment.
Contraindications
There are a number of diseases in which Curantil manifests its contraindications. Side effects in this case will be much more pronounced, which must be taken into account. These ailments include angina pectoris, especially in an unstable state. Atherosclerosis and chronic heart failure, hypertension and arrhythmia, gastric ulcer and duodenal ulcer, renal and hepatic failure, any of these diseases is a reason to refuse to take the drug and inform the doctor about your decision. Perhaps he can find an alternative. Do not forget about the possibility of individual intolerance.
Side effects
Very often, women note that while taking the drug, they feel a severe headache. Someone decides to continue taking it because the instructions say that gradually the symptoms will get weaker. Others immediately refuse further use of the drug. In fact, it will be correct to pause the appointment and tell the doctor about your feelings.
In addition to headache, a woman may experience severe dizziness and arterial hypertension, bouts of nausea and vomiting, tachycardia and angina pectoris. Quite often, hot flashes resembling climacteric ones are observed. All this can cause the drug, which is prescribed to expectant mothers even without preliminary examination, and its name is "Curantil". In the reviews, side effects are described in some detail, and they almost completely repeat the information contained in the instructions.
In rare cases, increased bleeding was noted. This is a serious side effect that makes surgery of any complexity impossible. To avoid this, you must adhere to the prescribed dosage. Sometimes doctors recommend reducing the single dose, but they are in no hurry to refuse to take it. Meanwhile, more and more people are abandoning the practice of using "Curantil", because if there is a need for surgical intervention, then the action of the drug will complicate the work of the surgeon.
Drug dosage
It is determined individually, depending on the diagnosis and condition of the woman. Side effects of "Curantila 25" are less pronounced, since they have less effect on the body. To test the body's response, the doctor may start with one tablet a day and gradually work up the dosage to three.
If heart failure or cerebral circulation disorders in the expectant mother are considered, then the dosage is increased. In this case, Curantil 75 is used three times a day. Side effects in this case should be monitored by the attending physician several times a week. At any time, doctors can interrupt treatment with this drug. The duration of the course will depend on a number of parameters, the motor activity of the fetus, its growth and enlargement of the uterus.
Other drugs during pregnancy
There are other medications that can be used during pregnancy. Most often, "Actovegin" is used, which improves the accelerating regenerative and metabolic processes. But it also has its own side effects. A good and reliable remedy is "Phlebodia". The medicine stimulates blood circulation, including in the placental circle. However, its use for pregnant women is limited because there are no reliable studies.
Another good drug of similar action is Cardiomagnil. It thins the blood and is therefore prescribed for thrombosis. However, it does not affect the immune system, and therefore is most often used together with Curantil. If your doctor strongly recommends that you take one of these drugs, ask for reasons for his decision and again remind you of existing chronic diseases. Discuss the potential benefits and harms together and make a decision.
Content
To increase immunity, thin blood, prevent blood clots, doctors prescribe a medicine called Curantil - instructions for use are attached in each package. A characteristic medication in an acceptable concentration normalizes coronary circulation, prevents placental insufficiency, and is excellent for the treatment of influenza and ARVI. The effective medicine Curantil is prescribed by the attending physician, superficial self-medication is completely excluded.
Curantil tablets
This drug belongs to the pharmacological group of antiplatelet agents, immunomodulators. It is produced in the form of round yellow-green tablets, intended for oral administration. According to the instructions for use, Curantil has antiplatelet, vasodilating and immunomodulatory properties. In the first case, we are talking about the prevention of thrombosis, in the second - about the vasodilator effect, in the third - about the intensive production of natural interferon. In a flu epidemic, such a pharmacological appointment is also appropriate.
Composition and form of release
Curantil is available in the form of tablets and dragees, has a different concentration of the active ingredient. Each pill contains 25, 50, 75 or 100 mg of dipyridamole, packaged in blisters of 10 pieces. This is the name of the active substance, the permissible concentration of which provides a stable therapeutic effect. Other components of the chemical composition of Curantil, according to the instructions for use, are presented below:
Pharmacodynamics and pharmacokinetics
In case of circulatory disorders, if there is a thrombus formation, doctors recommend taking the medicine Curantil. After penetration into the digestive system, the active components act systemically. The therapeutic effects of inhibitors are directed to the vessels:
- the elasticity of the vascular walls increases;
- the patency of the coronary vessels is normalized;
- blood pressure stabilizes;
- the speed and volume of blood flow increases;
- prevention of hemorrhagic complications is guaranteed;
- placental circulation returns to normal;
- ensured effective prevention of premature aging of the placenta;
- prevention of severe conditions associated with fetal hypoxia.
According to the instructions, you should take Curantil tablets whole, without chewing. The action of the active components is observed directly in the stomach. An hour after ingestion, the maximum concentration of the active component in the blood is observed, the metabolic process occurs directly in the liver, inactive metabolites are excreted through the intestines, kidneys with urine.
Indications for use
Doctors recommend patients with impaired cerebral circulation to complete the full course of Curantil. The medicine can be prescribed independently or in combination, the frequency of oral administration is negotiated individually, general recommendations are indicated in the instructions. According to the instructions for use, positive dynamics from Curantil tablets for the patient's body is observed when:
- ischemic cerebral circulation disorders;
- exacerbation of varicose and arterial thrombosis;
- discirculatory encephalopathy;
- microcirculation disorders and complications of such conditions;
- prevention of arterial hypertension;
- coronary heart disease, when the patient does not tolerate acetylsalicylic acid;
- viral diseases such as ARVI, influenza;
- heart valve replacement surgery;
- viral infections of various etiologies;
- placental insufficiency during pregnancy.
How to take Curantil
Oral administration of the drug is not associated with food, therefore, take pills on an empty stomach. Do not chew a single dose and do not first grind it into powder, drink it with plenty of water, other unsweetened liquid. The daily dosage of Curantil, according to the instructions for use, depends on the concentration of the active ingredient in each tablet and the diagnosis made by the doctor. Here are some valuable guidelines for patients:
- with ischemia of the heart, 75 mg three times a day;
- to improve blood circulation, 25 mg d 3-6 times a day;
- to reduce platelet aggregation 75-225 mg per day;
- for the prevention of influenza and ARVI, 2 tablets (75 mg) per day - in the morning and in the evening;
- for pathogenic infections, 75 mg three times a day.
special instructions
Since the effect of the drug is associated with a decrease in blood pressure, it is advisable to abandon driving vehicles, performing work with power mechanisms, and intellectual activity for the period of treatment. Before using dipyridamole as part of complex therapy, it is shown to consult with the attending physician, to study drug interactions.
Curantil during pregnancy
If disturbances in blood flow are observed during gestation, this is a condition that is dangerous for intrauterine development. A child in the womb suffers from oxygen starvation, and progressive hypoxia can significantly harm his health, from the first days of life, turn him into an incurable invalid. To restore the placental blood flow in full, it is required to take, according to the instructions, the medicine Curantil. A characteristic medication will dilate the blood vessels of the placenta, restore normal blood circulation - the bond between mother and child.
In childhood
Instructions for use inform that Curantil tablets and pills are contraindicated in childhood. They can already be used for their intended purpose by adolescents, starting from the age of 12 years. This medicine significantly improves blood circulation, but it is important to beware of bleeding, the risk of which is especially high in childhood. Before starting the treatment and prophylactic course, it is shown to consult with the local pediatrician.
Drug interactions
The Curantil drug is involved in a complex treatment regimen, and it can be used simultaneously with several pharmacological groups. Doctors do not exclude such associations, however, it is important not to forget the prevailing drug interactions. Special instructions are described in the detailed instructions for use, presented below:
- Preparations containing caffeine and diuretin significantly reduce the therapeutic effect of Curantil tablets.
- In combination with anticoagulants and aspirin, the risk of bleeding increases significantly, so the recommended doses must be reduced.
- When treating Alzheimer's disease, dementia, myasthenia gravis, Curantil's therapeutic effect is noticeably weakened.
- In combination with antibiotics of the cephalosporin series, a steady increase in the antiplatelet properties of Curantil is observed.
- The action of antihypertensive drugs in combination with a characteristic medication enhances its therapeutic effect.
- It is better not to combine the use of nitroglycerin with Curantil tablets, since blood pressure pathologically decreases to a critical minimum.
- Antacids in combination with Curantil reduce the absorption of the latter, weaken the stable therapeutic effect.
- Active ingredients Curantil can weaken the anticholinergic effects of cholinesterase inhibitors.
- The specified drug in combination with xanthine derivatives, prevailing in tea, coffee, reduce the overall therapeutic effect.
Side effects and overdose
Curantil tablets improve blood microcirculation, increase the elasticity of cerebral vessels, however, oral administration can significantly harm health. At the very beginning of the course, side effects are not excluded, which reduce the quality of life, prevent the patient's early recovery. Potential anomalies, according to the instructions for use, are as follows:
- instability of the heart rhythm: arrhythmia, tachycardia;
- signs of dyspepsia: abdominal pain, flatulence, diarrhea;
- instability of the central nervous system: migraines, dizziness;
- skin rashes of varying intensity;
- rhinitis, middle ear congestion.
Contraindications
The detailed instructions for use indicate medical restrictions that reduce the list of patients, potential buyers. The characteristic medication is not suitable for improving microcirculation in the following clinical pictures:
- unstable angina;
- acute phase myocardial infarction;
- hepatic and renal failure;
- decompensation stage heart failure;
- arterial hypotension, collapse;
- subaortic aortic stenosis;
- hypersensitivity to active ingredients.
Terms of sale and storage
Curantil is sold in every pharmacy, dispensed by pharmacists without a prescription. When buying, you must strictly observe the expiration date, not violate the recommendations of a specialist, read the instructions for use. It is better to store the medicine in the refrigerator, to avoid contact of the tablets with small children. Reviews on the use of the drug are left not only by patients, but also by the attending physicians.
Kurantil's analogs
The 75 mg drug is not cheap, so many patients prefer the cheaper conservative treatment. When choosing a reliable analogue of Kurantil, it is recommended to pay attention to such medicines:
- Parsedil;
- Trombonyl;
- Dipyridamole;
- Coribon;
- Apricor;
- Persantine;
- Anginal.
Curantil's price
The cost of the medication in the pharmacy is overpriced, so the purchase will be cheaper if you order the medication via the Internet. There you can also find reviews about the treatment with Curantil. Here are the approximate prices in pharmacies.
During pregnancy, especially in its early stages, women are prescribed the drug Curantil, which many mistaken for a vitamin complex, but in fact, this is a drug that launches many processes in a woman's body. It is worth taking such a drug only as directed by a doctor, then it will not harm either the future baby or the mother's health. The negative and positive properties of Curantil will be described below.
Is Curantil necessary during pregnancy and why is it prescribed?
Whether or not to take medications during pregnancy has always caused a lot of controversy, but the main thing in making a decision will be the amount of studied information about the drug. A good doctor will always calm the patient down, tell you what this or that drug is used for, but what is Curantil prescribed for?
Curantil (in other words, its analogue Dipyridamole) is a drug often prescribed by doctors during pregnancy, but expectant mothers confuse it with vitamins for pregnant women. This drug has a very complex effect on the body of the expectant mother, and it is prescribed only in case of impaired blood circulation. The composition of Curantil includes its analogue Dipyridamole - a biologically active substance that saturates cells with oxygen.
According to doctors, unlike many drugs, Curantil has a beneficial effect on the placenta, in addition, it reliably protects the health of a pregnant woman and prevents the appearance of edema, pressure, migraine, and viral diseases.
Often, Curantil is prescribed in courses, or during pregnancy. Curantil, significantly reduces the risk of blood clot formation by regulating blood outflow, has a positive effect on the immune system, reduces the congestion of internal organs, thins the blood, helps to strengthen blood vessels, despite the many advantages, the instructions for its use are very simple: take the drug on an empty stomach one hour before eating , and the dosage is 1 tablet.
Like any medicine, Curantil has side effects on the body:
- Diarrhea, nausea, vomiting;
- Tachycardia;
- Dizziness, migraine;
- Allergy expressed on the skin;
- Arthralgia.
Contraindications for taking Curantil:
- Hypersensitivity to the components of the drug;
- Myocardial infarction;
- Diseases that expose the body to bleeding;
- Unstable heartbeat;
- Severe arrhythmia;
- Heart failure.
Instructions for the use of Curantila during pregnancy
Curantil medicine has a large list of side effects on the body. The likelihood of allergies is enormous, so it is important to be extremely careful and take the drug according to the prescribed dosage.
In the early stages, that is, in the first trimester, Curantil is prescribed quite often. Sometimes it is recommended to drink it in the last trimester, or before the planned pregnancy.
Pregnant women are very worried about the prescription of medications by the doctor. Curantil (aka Dipyridamole) quickly thins the blood, but this drug is best taken under the supervision of doctors and only if there are indications for its use.
Before taking Curantil, you need to carefully study the instructions for taking it. In this regard, you need to be very careful, since very few trials of Curantil were carried out and abroad it is prescribed as rarely as possible. That is why, when prescribing Curantila by a doctor, it will be reasonable to require clear explanations of this decision, so as not to harm, since, despite the positive reviews, each organism is individual, and, accordingly, the reactions to the reception are different.
Often, Curantil is prescribed by doctors for premature aging of the placenta, but this is not always the case; in many cases, doctors recommend taking it to prevent various acute complications, since the female body is very heavily loaded during pregnancy.
- Preventing the appearance of plaques;
- Strengthening blood vessels;
- Blood thinning;
- Strengthening the immune system;
- Improving blood circulation;
- Eliminates the appearance of hemorrhoids;
- Improves kidney function;
- Prevention of seizures;
- High blood pressure;
- ARVI prevention;
- Toxicosis in the later stages;
- Puffiness;
- Strengthening the placenta.
In many cases, Curantil is prescribed by a doctor for prophylaxis, but it is worth making sure that taking the drug without taking the drug will certainly begin to develop some kind of disease. In the instructions for use, the dosage of taking Curantil is prescribed, but often the doctor himself prescribes the amount of medication taken.
The dosage prescription depends on the following indicators:
- The results of the tests passed;
- Indications for the use of this drug;
- Dates of pregnancy.
Taking the drug on your own without a doctor's prescription is not recommended, even if it was prescribed earlier, as this can harm the health of the mother and child.
Curantil during pregnancy: drug reviews
The question of whether taking the drug Curantil really helps to thin the blood, strengthen the immune system, migraine, edema remains relevant to this day. In the later stages (in the third trimester), Curantil is rarely prescribed.
In case of individual intolerance, Curantila can be replaced by taking the drug Actovegin, for which the indications for use are very similar, moreover, it can be prescribed in the form of a dropper, but has rather different effects.
Reviews about taking Curantila:
- Olga: I was taking Curantil on an empty stomach, eventually found that my head was spinning. The doctor said it should be taken with meals.
- Galina: I passed blood tests, it turned out that the blood density increased, I was taking Curantil, everything is fine, I feel great.
- Sveta: I don't know how much others drink it, but I drank until 12 weeks! And I had a very bad headache from him, after taking it it passed.
- Ira: Saw Curantil from the 20th week, gave birth to an excellent healthy baby.
- Anna: I have been drinking since 34 weeks, everything is fine, no edema was found on the ultrasound.
- Olegovna: The doctor prescribed Curantil, but I practically did not take it, because I drink a pill and the weakness is severe, according to the ultrasound, a large fetus was found and Curantil was canceled.
- Zhanna: Curantil was discharged for indications of impaired blood flow in the placenta, three days after taking it, everything returned to normal.
- Gita: They wrote out Kurantil for a cold, helped a lot, after 5 days all the signs of a viral disease disappeared, now the children are sick, but I am not.
- Amalia: Who has not drunk Curantil for cystitis? A great thing I want to tell you, I drink once a year and forget about inflammation for a long time.
- Evgeniya: I was taking Curantil, everything is fine, they prescribed to prevent fetal hypoxia.
- Elizaveta: I took Kurantila both in the first and in the second pregnancy, everything is fine, the children are growing up to the delight of their mother.
- Ulya: We discovered a suspicion of chorion detachment, prescribed Curantil, the state of health is excellent, the main thing is not to inspire myself with anything.
- Natalie: Usually Curantil is used in a heap with some means, I was prescribed to prevent fetal hypoxia, now everything is fine, there were no side effects, the result of which was sought.
- Elya: The doctor prescribed Curantil during the first trimester, but I was so bad that I had to cancel his reception on my own, the tests were fortunately excellent, but it was not worth doing this on my own, this was my first pregnancy, I did not understand how I risked.
Existing analogues of Curantil
Curantil has about 15 analogues, among which not all are on sale. Pentoxifylline, one of the Kuransil analogs, is available in the form of a tablet or ointment, a drug very similar in its mechanism of action, which is prescribed to be used until childbirth. It has a beneficial effect on the development of the fetus and reduces the risk of its loss, increases the tone of the uterus, but does not particularly affect the pressure, therefore, practically does not affect the development of hypoxia in the child. Basically, Pentoxifylline treats rapidly emerging acute conditions in pregnant women. Despite all its positive qualities, Pentoxifylline has almost the same side effects as Curantil.
Other analogues of Curantil:
- Trombonyl;
- Dipyridamole - Ferein;
- Parsedil;
- Sanomil - Sanovel;
- Vero - Dipyridamole.
Before taking an analogue of Curantil, you must make sure that analogs are allowed to be taken during pregnancy and only with the permission of the attending physician.
Side effects of Curantila
Curantil is significantly different from its counterparts. Despite its positive effect on the course of pregnancy, the side effects of the drug can be harmful to health. Sometimes you have to take Curantil for a long time, in several courses, especially with high blood pressure. Improvements in well-being with Curantile are observed for 3-5 days, since its benefit is mainly to improve the blood circulation rate. When the appointment of Curantila, or its analogues, takes place, a special approach to the body of a pregnant woman is needed: test results, well-being, possibly ultrasound indications or screening.
In case of an overdose, individual intolerance or simple intake of Curantil, such side effects are likely to occur:
- Muscle pain;
- Bradycardia;
- Joint pain;
- Redness of the skin of the face;
- There is also noise in the auricles;
- Runny nose;
- Stomach ache;
- General weakness;
- Stool disorder;
- Low blood pressure.
Curantil tablets: facts about taking
Curantil tablets are prescribed to improve blood flow, as well as raise the placenta. The duration of admission depends on both the doctor's prescription and the woman's well-being. In second place after Curantil is its analogue Dipyridamole. Dipyridamole and aspirin in the complex are primarily drugs that prevent heart attacks and strokes. Complaints of some women after some time while taking Curantil say that one of its side effects is bleeding, which can provoke an overdose.
A few facts about taking Qurantile:
- If your stomach hurts within a week of taking Curantil, you need to consult a doctor and most likely cancel the intake;
- Curantil is a very effective medicine for hemorrhoids;
- Curantil and boron uterus contribute to the good treatment of hyperplasia;
- To maintain pregnancy, Curantil and Iodomarin are prescribed;
The pregnancy hormone progesterone thickens the blood, and Curantil dilutes it.
Good Curantil tablets: why
Curantil tablets as a reliable way to prevent the exacerbation of chronic diseases of a pregnant woman. Curantil lowers blood pressure, helps prevent placental insufficiency. However, there is a very good analogue of it, which does not dilate the blood vessels of the heart - this is Trental. Analogues are cheaper, and they have, oddly enough, fewer contraindications, but often manufacturers put a ban on them for use by pregnant women. A feature of Curantil's treatment is that it relieves a pregnant woman from toxicosis in a few days.
Factors of a positive effect on taking the drug Curantil:
- Compliance with all recommendations of the obstetrician;
- Correct lifestyle;
- Proper nutrition.
Why is courantil prescribed during pregnancy (video)
Kurantil, according to its indications and reviews, is not a bad drug, but you should not self-medicate, but rather turn to a specialist who is interested and will help the successful course of pregnancy.
Antiplatelet agent. Immunomodulator
Active substance
Dipyridamole
Release form, composition and packaging
Curantil 25
Film-coated tablets from yellow to greenish-yellow in color, round in shape with a smooth uniform surface.
Excipients: corn starch - 11.75 mg, lactose monohydrate - 11 mg, magnesium stearate - 1.25 mg, talc - 0.5 mg, gelatin - 1 mg, colloidal silicon dioxide - 0.5 mg.
Dragee shell composition: sucrose - 24.314 mg, calcium carbonate - 3.796 mg, magnesium hydroxycarbonate - 1.322 mg, talc - 1.322 mg, macrogol 6000 - 1.536 mg, liquid dextrose (dry weight) - 1.456 mg, titanium dioxide - 1.024 mg, polyvidone (K value = 25 ) - 0.213 mg, carnauba wax - 0.011 mg, quinoline yellow dye (E104) - 0.006 mg.
100 pieces. - bottles of colorless glass (1) - packs of cardboard.
Excipients: corn starch - 67.75 mg, lactose monohydrate - 28.5 mg, gelatin - 2.5 mg, sodium carboxymethyl starch (type A) - 3.75 mg, colloidal anhydrous silicon dioxide - 1.25 mg, magnesium stearate - 1.25 mg.
Film casing composition: hypromellose - 0.9 mg, talc - 0.4 mg, macrogol 6000 - 1.2 mg, titanium dioxide (E171) - 0.1 mg, quinoline yellow dye (E104) - 0.008 mg, simethicone emulsion - 0.002 mg.
120 pcs. - bottles of colorless glass (1) - packs of cardboard.
Curantil N 75
Film-coated tablets yellow, round, flat-cylindrical.
| 1 tab. | |
| 75 mg |
Excipients: corn starch - 33.75 mg, lactose monohydrate - 12.5 mg, sodium carboxymethyl starch (type A) - 3.75 mg, gelatin - 2.5 mg, colloidal anhydrous silicon dioxide - 1.25 mg, magnesium stearate - 1.25 mg.
The composition of the film shell: hypromellose - 0.9 mg, talc - 0.4 mg, macrogol 6000 - 0.12 mg, titanium dioxide (E171) - 0.1 mg, quinoline yellow dye (E104) - 0.01 mg, simethicone emulsion - 0.002 mg.
20 pcs. - blisters (2) - cardboard packs.
pharmachologic effect
Myotropic vasodilator. Has an inhibitory effect on platelet aggregation, improves microcirculation.
Dipyridamole dilates arterioles in the coronary bloodstream, when taken in high doses - and in other parts of the circulatory system. However, unlike organic nitrates and calcium antagonists, the expansion of the larger coronary vessels does not occur.
The vasodilating effect of dipyridamole is due to two different mechanisms of inhibition: inhibition of adenosine uptake and inhibition of phosphodiesterase.
In vivo, adenosine is found at a concentration of approximately 0.15-0.20 μmol. This level is maintained thanks to the dynamic balance between ejection and recapture. Dipyridamole inhibits the uptake of adenosine by endothelial cells, erythrocytes and platelets. After the introduction of dipyridamole, an increase in the concentration of adenosine in the blood and an increase in adenosine-mediated vasodilation are found. At higher doses, platelet aggregation caused by adenosine is inhibited, and the tendency to thrombus formation decreases.
The breakdown of cAMP and cGMP, which suppress platelet aggregation, occurs in platelets under the action of the corresponding phosphodiesterases. At high concentrations, dipyridamole inhibits both phosphodiesterases, at therapeutic concentrations in the blood - only cGMP-phosphodiesterase. As a result of stimulation of the corresponding cyclases, the power of cAMP synthesis increases.
As a pyrimidine derivative, dipyridamole is an inducer and has a modulating effect on the functional activity of the interferon system, increases the decreased production of interferon alpha and gamma by blood leukocytes in vitro. The drug increases nonspecific resistance to viral infections.
Pharmacokinetics
Absorption and distribution
After a single oral dose of 150 mg, C max of dipyridamole in plasma averages 2.66 μg / l and is achieved within 1 hour after administration.
Dipyridamole is almost completely bound to plasma proteins. Dipyridamole accumulates in the heart and in erythrocytes.
Metabolism and excretion
Dipyridamole is metabolized in the liver by binding to glucuronic acid. T 1/2 is 20-30 minutes. It is excreted in the bile in the form of a monoglucuronide.
Indications
- treatment and prevention of ischemic cerebral circulation disorders;
- encephalopathy;
- primary and secondary prevention of ischemic heart disease, especially with intolerance;
- prevention of arterial and venous thrombosis and treatment of their complications;
- prevention of thromboembolism after heart valve replacement surgery;
- prevention of placental insufficiency in complicated pregnancy;
- microcirculation disorders of any type (as part of complex therapy);
- prevention and treatment of influenza, ARVI (as an interferon inducer and an immunomodulator) - for taking the drug at a dose of 25 mg.
Contraindications
- acute myocardial infarction;
- unstable angina pectoris;
- common stenosing atherosclerosis of the coronary arteries;
- subaortic aortic stenosis;
- heart failure in the stage of decompensation;
- arterial hypotension;
- collapse;
- severe arterial hypertension;
- severe heart rhythm disturbances;
- chronic obstructive pulmonary disease;
- chronic renal failure;
- liver failure;
- hemorrhagic diathesis;
- diseases with an increased risk of bleeding (including peptic ulcer of the stomach and duodenum);
- hypersensitivity to the components of the drug.
Dosage
The dose of the drug is selected depending on the severity of the disease and the individual response of the patient.
For prevention and treatment of cerebrovascular accidents, and for prevention appoint 75 mg 3-6 times / day. The maximum daily dose is 450 mg.
For reduce platelet aggregation Curantil is prescribed at a dose of 75-225 mg / day in several doses. In severe cases, the dose may be increased to 600 mg / day.
For prevention of influenza and ARVI, especially during epidemics, Curantil N25 and Curantil 25 are prescribed 50 mg (2 tablets or 2 tablets) / day in 1 reception. The drug is taken once a week for 4-5 weeks.
For prevention of recurrence of acute respiratory viral infections in patients who often suffer from respiratory viral infections Curantil N25 and Curantil 25 are prescribed at 100 mg / day (2 tablets or pills 2 times / day with an interval between doses of 2 hours). The drug is taken once a week for 8-10 weeks.
The tablets should be taken on an empty stomach, without breaking or biting, with a small amount of liquid. The duration of the course of treatment is determined by the doctor.
Side effects
On the part of the cardiovascular system: palpitations, tachycardia (especially with the simultaneous use of other vasodilators), bradycardia, flushing of the face, flushing of the facial skin, coronary steal syndrome (when using the drug at a dose of more than 225 mg / day), lowering blood pressure.
From the digestive system: nausea, vomiting, diarrhea, epigastric pain. Usually, these side effects disappear with longer use of the drug.
From the side of the blood coagulation system: thrombocytopenia, changes in the functional properties of platelets, bleeding; in isolated cases - increased bleeding during or after surgery.
From the side of the central nervous system: dizziness, noise in the head, headache.
Allergic reactions: skin rash, urticaria.
Others: weakness, feeling of ear congestion, arthritis, myalgia, rhinitis.
When using the drug in therapeutic doses, side effects are usually mild and transient.
Overdose
Symptoms: lowering blood pressure, angina pectoris, tachycardia, hot flashes, weakness and dizziness.
Treatment: artificial vomiting, gastric lavage, the appointment of activated carbon. The vasoconstrictor effect of the drug can be stopped by slow (50-100 mg / min) intravenous administration of aminophylline. If the symptoms of angina pectoris persist, sublingual nitroglycerin is prescribed.
Drug interactions
With the simultaneous use of Curantil with anticoagulants or acetylsalicylic acid, the antithrombotic effect of the latter increases and, accordingly, the risk of developing hemorrhagic complications.
With simultaneous use, Curantil enhances the effect.
When used together, Curantil can weaken the anticholinergic effects of cholinesterase inhibitors.
With simultaneous use, xanthine derivatives weaken the vasodilating effect of Curantil.
special instructions
With the simultaneous use of tea or coffee (contain xanthine derivatives), the vasodilating effect of Curantil may decrease.
Use in pediatrics
Influence on the ability to drive vehicles and control mechanisms
Caution should be exercised when driving vehicles and operating mechanisms, since as a result of a fall in blood pressure while taking Curantil, the ability to concentrate and speed of psychomotor reactions may deteriorate.
Pregnancy and lactation
It is possible to use the drug during pregnancy if indicated.
The use of the drug during lactation is possible only if the expected benefit from treatment outweighs the possible risk.
With impaired renal function
Contraindicated in chronic renal failure
For violations of liver function
Contraindicated in liver failure
Conditions of dispensing from pharmacies
The drug is available with a prescription.
Storage conditions and periods
List B. The drug should be stored in a dark place, out of the reach of children, at a temperature not exceeding 30 ° C. Shelf life Kurantila N 25 and 3 years, Curantila 25 - 5 years.
Often there are cases when the doctor prescribes Curantil during pregnancy for various reasons: kidney failure after childbirth, high blood pressure, headaches, swelling, convulsions. There is a lot of controversy around this tool, so you need to find out the maximum amount of information about it.
For prophylaxis, taking the drug Curantil
pregnant doctor examining
doctor's nursing exercise
Usually the doctor always explains why you need this or that medication, because the use of a medication can be dangerous for a woman and her baby. The drug will not harm only if you strictly follow the instructions. Kurantil, when planning a pregnancy and while carrying a baby, relieves a girl of many problems.
The tool belongs to the group of immunomodulators and antiplatelet agents. It is prescribed for the prevention of encephalopathy, circulatory disorders in the brain. The tool prevents blood clots from forming and significantly increases immunity. Available in the form of tablets and pills.
For the prevention of circulatory disorders in the brain
When planning pregnancy, Curantil acts as follows:
- begins to bind to plasma proteins;
- accumulates in erythrocytes and heart;
- decomposes in the liver;
- excreted from the body with bile.
The tool does not allow the biologically active substance adenosine, which is formed in the body, to break down. Moreover, adenosine increases its amount of blood, namely, it promotes the expansion of small vessels responsible for blood flow. The vessels supply the organs with nutrients and oxygen.
This is necessary so that the girl does not have high blood pressure, headaches and swelling, which often begin due to a violation of the blood capillaries.
When can I take the remedy
During pregnancy in the 1st trimester, Curantil is rarely prescribed to improve uteroplacental blood flow, because the load on the vessels of these organs is still low. If a woman does not have serious illnesses, her circulatory system will cope with this load. Sometimes, when planning a pregnancy, the doctor prescribes courantil if the woman's coagulogram shows a strongly increased blood clotting ability.
Thrombosis of all vessels is very undesirable for the expectant mother and fetus. This disease can even be dangerous in its consequences, therefore this medicine is prescribed to raise immunity. It promotes the production of interferon, which actively affects viruses. Interferon perfectly protects a woman's body from ARVI, which is very important, especially if the first trimester is in spring or autumn.
It does not hurt to know what exactly the popular chime is prescribed for during pregnancy in the 2nd and 3rd trimesters. The fact is that by this time you need to be especially careful about the state of the vessels of the uterus and placenta. At this stage of bearing a child, the immunizing properties of the drug are not so important, because the baby is practically formed, and the woman's body is already used to a new state for itself. However, the vessels of the uterus begin to feel the load from the fetus, which needs more nutrients and oxygen.
You must strictly adhere to the instructions when taking the drug.
To avoid thrombosis of the placental and uterine arteries, you need to regularly monitor the coagulogram indicators. First of all, it is worth paying increased attention to the state of the vessels of the uterus and the vessels of the placenta. Of great importance is the speed with which blood flows through the arteries of the umbilical cord from the placenta to the baby. It is also important to assess the diameter of the vessel lumen. In any case, during pregnancy, be sure to check with your doctor why he prescribes chime. While carrying a child, you need to know absolutely everything about your state of health.
Danger of taking medication
During pregnancy, you must strictly follow the instructions for taking chirantil. Taking the drug uncontrolled can cause serious complications. It is contraindicated if a woman has severely low or high blood pressure, abnormalities in the functioning of the liver, kidneys, and heart. In addition, the drug is prohibited for the following diseases:
- arterial hypotension;
- subaortic stenosis;
- unstable angina;
- severe arrhythmias;
- acute myocardial infarction;
- chronic heart failure;
- hemorrhagic diathesis;
- severe arrhythmias;
- stomach ulcer;
About an hour after the drug is consumed, its maximum concentration is formed in the blood. Therefore, you should know that the medicine does not combine with caffeine. Drinking too much tea or coffee can reduce the effect of the pills. Even if you strictly follow the dosage of curantil during pregnancy, side effects are not excluded.
If you follow your doctor's orders strictly, the medication will not harm the fetus. Read the packaging carefully and do not confuse the 75 and 25 gr products. Curantil tablets are prescribed at any stage of pregnancy, there are no restrictions. However, negative reactions can occur even if you follow the instructions. But in this case, they will be expressed slightly.
If you have confused the dosage of the remedy, you need to urgently call the doctors, and before their arrival, wash the stomach. When you exceed the dosage of courantil during pregnancy, the "reward" will be strong side effects. These include.
- Rapid pulse.
- The appearance of bradycardia and tachycardia.
- Pain in muscles and joints.
- Ear congestion.
- Drowsiness, weakness.
- Severe coryza.
- The appearance of allergies in the form of a rash, urticaria, itching.
- Increased headaches, dizziness.
- Abdominal pain, diarrhea, nausea, vomiting.
- A sharp rush of blood to the face.
The drug has both positive and negative sides. Therefore, you do not need to self-medicate. Only the doctor should prescribe the medicine.
Instructions for use
During pregnancy, it is imperative to check with your doctor how to drink chime. Usually, a 25 mg tablet is taken three times a day. There is a dosage of 75 mg, but in this case it is necessary to use a different treatment regimen, and the dosage should be lower.
Usually, during pregnancy, doctors prescribe courantil in 25 mg tablets, rather than 75 mg. It's not about the price. It's just that such a large dosage can harm a woman.
The remedy is taken on an empty stomach one hour before a meal or two hours after a meal. The tablet is not chewed, but swallowed, after which it must be washed down with water. If there is an overdose of the drug, and side effects appear, you should immediately stop taking the medication and call your doctor.
It must be taken strictly as directed by a doctor
Do not ignore the doctor's advice on how to properly take courantil in any trimester of pregnancy. Some girls think that if they reduce the dosage of the medicine and take it less often than the doctor recommends, then there will be no negative impact on the baby, and the side effects will disappear. This opinion is erroneous, so you need to strictly follow the doctor's prescriptions when you take courantil during pregnancy, and read the instructions for use.
Sometimes chime is necessary when planning pregnancy if a woman has high blood clotting, manifestations of varicose veins. For prophylaxis, 25 mg tablets are usually prescribed twice a day.
Larisa Kozhevnikova:
She took chimes when carrying her first pregnancy. I read a lot of reviews after the doctor prescribed this medicine for me, so I was calm. High pressure saw. It returned to normal, fortunately, otherwise I was very worried about this.
Alisa Bespalova:
She took chimes when planning her second pregnancy. I heard many reviews from girlfriends that you need to strictly observe the dosage, otherwise there will be side effects. She was treated for venectomy and, despite all the warnings, mixed up the dosage of the pills. Severe vomiting began, a terrible headache, they took me away in an ambulance. I had to prescribe another medicine, so I can't say if it helped or not.
Julia Panchina:
I took chimes during pregnancy, because the price was fine, and I already spent a lot of money on my health. The doctor advised me to do it when my son began to hiccup at 35 weeks. After the treatment, the blood began to circulate better and the problem disappeared.
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